Biotin (B7) Flashcards
1
Q
How is biotin absorbed in the body
A
It is found in food as either Biotin or Biocytin (bound to lysine)
Biotinidase unbinds biotin for absorption
Free biotin is absorbed by active transports
Eggs/meat sources have greater bioavailability
2
Q
What is the active form of Biotin?
A
Generally bioactive as Biotin
3
Q
What are the functions of Biotin?
A
Required in carboxylation reactions: coenzyme of carboxylase enzymes
Required for metabolism of carbs, fats and proteins
Required for the catabolism of BCAAs
Involved in DNA folding
4
Q
What is causes by a Biotin deficiency?
A
- Skin rash
- Patchy hair loss
- Convulsions
Mainly due to biotinidase enzyme deficiency
Excessive consumption of raw egg whites
5
Q
What are good food sources of Biotin?
A
- Chicken liver
- Eggs
- Chicken nuggets
- Peanuts