Manganese Flashcards
1
Q
How is Manganese absorbed?
A
In small intestine via diffusion and active transport
only 5-10% absorbed
Depends on iron status
- more iron = less manganese
2
Q
What is the name of the transport protein for manganese?
A
Alpha-2-macroglobulin
3
Q
What are the functions of manganese?
A
- cofactor in gluconeogenesis
- cofactor for superoxide dismutase (antioxidant defence)
- cholesterol synthesis
- urea synthesis
- cofactor to enzymes involved in proteoglycan
4
Q
what is caused by a copper deficiency?
A
- poor growth and development
- poor glucose metabolism
- skeletal abnormalties
5
Q
What is caused by copper toxicity?
A
- severe neurological impairment
occurs with supplementation
6
Q
What are good sources of copper?
A
- walnuts and peanuts
- pineapple
- lima beans
