Potassium Flashcards
How is potassium absorbed?
90% absorbed in small and large intestines by either passive diffusion or Na/K pump
Where is potassium stored?
95% stored inside cells
Uptaken by active transport
How is potassium excreted?
Mostly in urine and small amounts in faeces and sweat
Regulated by aldosterone
What are the functions of potassium?
- major cation in intracellular fluid
- contractility of smooth, skeletal and cardiac muscle
- excitability of nerve tissue
- high potassium intake reduces serum calcium excretion
- High potassium intake promotes sodium + water excretion, resulting in reduced blood volume, and
reduced blood pressure (main mechanism of DASH) - responsible for changing the membrane potential during depolarisation of the cell
What is caused by a deficiency of potassium?
Hypokalemia:
- cardiac arrhythmia and cardiac arrest
- muscle weakness
- fatigue
- irritation
- glucose intolerance
Usually due to profound fluid loss rather than lack of intake
What is caused by a toxicity of potassium?
Hyperkalemia:
- cardiac arrhythmia/ cardiac arrest
- muscle weakness
- temporary paralysis
- gastrointestinal ulceration
Does not occur through diet alone, use of supplements and potassium chloride
How does chronic kidney disease effect potassium intake?
Chronic kidney disease results in poor excretion of potassium so intake must be severely limited, which restricts many foods
What are good sources of potassium?
- potato with skin
- beans
- salmon
- milk
- banana
What is the DASH diet and what does it involve?
Dietary Approach to Stop Hypertension
- Sodium: 2300mg
- Potassium: 4700mg
- Calcium: 1250mg
- Magnesium: 500mg
all of these are higher than the NRVs (except Na)
Fibre: 30g
What does the DASH diet promote a high potassium to sodium ratio?
The aim of the high K:Na ratio is to promote the excretion of sodium, which in turn will cause water excretion, leading to decreased blood volume, and thus decreased blood pressure
What are the roles of magnesium and calcium in the DASH diet?
Calcium acts as a smooth muscle relaxant, so relaxes the smooth muscles of the arterial walls
Magnesium also acts as a vasodilator
What is the role of fibre in the DASH diet?
Fibre acts to bind cholesterol for excretion, to reduce the overall CVD risk
Also assists in appetite control which can help reduce weight and reduce hypertension