Visual System Physiology Flashcards
what are the photoreceptor cells connected to?
bipolar cells
what are bipolar cells connected to?
ganglion cells
the central processes coming off the ganglion cells form what?
the axons of the optic nerve which eventually end up in the nuclei of the brain
which system is heavily dependent on convergence?
rod system
why is convergence important in the rod system?
it allows the rod system to operate in dim light
where does the density of the cones peak at?
the fovea
where does the density of the rods peak at?
about 20 degrees to the side of the cones
what happens to the photoreceptor cells under dark conditions?
they depolarize
what happens to the photoreceptor cells under light conditions?
they hyperpolarize
what are rods and cones constantly releasing?
glutamate
when is glutamate release from the photoreceptor cells the highest?
when it is dark
when is glutamate release the lowest?
when there is light
when does glutamate act as an excitatory amino acid?
when the receptor is an NMDA or non-NMDA receptor
when does glutamate act as an inhibitory amino acid?
when the receptor is an mGlu6 receptor
what glutamate receptor do bipolar cells express?
mGlu6 receptor
what does the mGlu6 receptor do when it is activated?
it closes the cGMP-gated Na+ channel
what happens when the bipolar cell is activated?
it releases glutamate
what glutamate receptor is found on the ganglion cells?
NMDA or non-NMDA (so glutamate will act as an excitatory amino acid on the ganglion cells)
what is the most prominent target of the retina?
the lateral geniculate body
what is the role of the lateral geniculate body?
it regulates the flow of information to the primary visual cortex