vision Flashcards
macula
area of 95% of our vision
dark spot on eye images
when looking at a photo of the eye - what is the white spot
optical nerve
optical factors that affect VA
pupil size, refractive errors, clarity of optics
fovea
dense area of cones
centre of macula
where are there peak rods?
off-centre of macula
blind spot
no rods or cones
photopigments in rods & cones
rods: rhodopsin
(1 of 3): cone-opsins -> bind to Vit. A
vitamin A
receives signal & changes photopigment (like an antenna)
bound to rhodopsin & opsin
both rods and cones
phototransduction
photopigments have vitamin A attached
when light enters, 11-cis retinal becomes all-trans retinal (the kink straightens)
this results in a messenger cascade
rods vs cones
rods:
Night / BW vision
1 type
Absent from fovea
100 million
More sensitive
cones:
Day / Colour vision
3 types
Densest at fovea
5 million
Less sensitive
effect of light on photoreceptors
hyperpolarised
state of photoreceptors at night
depolarised due to continuous influx of sodium ions via cGMP
state of photoreceptors during day
cGMP -> GMP closes channel
No influx of sodium therefore hyperpolarised
passage of info within retina
photoreceptors -> bipolar cells -> ganglion cells
lateral interactions
horizontal cells (modify signal as it comes down, see things like flicker & edges)
amacrine cells