Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

PLE Microbiology > Viruses - RNA pos sense > Flashcards

Viruses - RNA pos sense Flashcards

You may prefer our related Brainscape-certified flashcards:
Biology 101 flashcards
1
Q

Picornavirus virus morphology

A

Naked RNA positive sense

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Transmission of picornavirus

A

Fecal oral route

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Proliferation of Positive sense virus

A

Viral RNA inserted in cell and host cell translate protein using own cell’s system

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Picornavirus protein product

A

Polyprotein cleaved by viral proteiases

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

RNA positive sense replication occurs in what dcell part

A

Cytoplasm

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Examples of Picornavirus

A

Hepatitis A
Enterovirus (poliovirus, echovirus, coxsackie virs)
Rhinovirus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Transmission of Polio and Replication

A

Fecal oral route, replicates in Peyer’s patches (2-3 weeks), then invasdes anterior horn of spinal cord

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Symptoms of polio

A

Asymmetric paralysis, myalgia, respiratory insufficiency from paralysis

Aseptic meningitis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Treatment of Polio

A

NONE - only vaccine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

OPV vs IPV

A

OPV - live attenuated, creates both IgG and IgA
IPV - killed
bypasses GI tract, forms IgG not IgA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Coxsackie A vs B

A

A - Hand, foot, and Mouth Disease - red vesicular rash
Viral meningitis
Summer months

B - dilated cardiomyopathy, Devil’s grip, Bornholm disease, pleurodynia - sharp pain on chest

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Unique features of rhinovirus compared to others picornavirus

A

Acid labnile. Cannot be transmitted fecal oral route

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Transmission of rhinovirus

A

Respiratory, attaches to ICAM-1 on host cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Rhinovirus grows in what temperatures

A

Cool temperatures, which is why ionfects upper respiratory tract

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Transmission of Hepatitis A

A

Fecal oral route, transmitted from infected feces contaminating water, shellfish

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Purifying techniques to avoid Hep A

A

Chlorinated,Bleached, UV radiation, bboiled

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Anicteric hepatitis in young children is caused by?

A

Hepatitis A

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Duration of illness in Hepatitis A

A

1 month self limiting, no carrier or chronic state

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Hepatitis A vaccine is what type?

A

Inactivated

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Calicivirus morphology

A

Positive Sense RNA virus, naked virus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Most common calicivirus

A

Norovirus (Norwalk)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

Norwalk manifestations

A

Diarrhea in crowded places, children, day care, schools, shellfish consumption

Explosive watery viral gastroenteritis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

Flavivirus structure

A

Enveloped RNA virus positive sense

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

Dengue is what kind of virus

A

Flavivirus

25
Q

Breakbone fever is also known as

A

Dengue

26
Q

Yellow fever vector

A

Aedesaegypti

27
Q

Symptoms of fyerllow fever

A

Backache, jaundice, bloody dioarrhea, hematemesis

28
Q

West nile virus reservoir

A

birds

29
Q

Symptoms of west nile virus

A

Encephalitis, myelitis, meningitis, seizures

30
Q

Vector of West nile virus

A

Culex

31
Q

Flavivirus examples

A

Hep C
Dengue
West Nile Virus
Yellow Fever

32
Q

Mechanism of antigenic variability in Hep C

A

3-5 exonuclease is noit proofread, so errors lead to antigentic variation

33
Q

Acute infection of Hep C marker

A

ALT rise and fall in 6 months, anti-HCV

34
Q

Chronic infection of Hep C marker

A

anti-HCV persists, cryoglobulin,

35
Q

Treatment of Hepatitis C

A

Ribavirin + IFN a,

36
Q

Two Examples of togavirus

A

Arbovirus, Rubella

37
Q

Three arbovirus examples

A

Western Equine, Venezuelan Equine, Eastern Equine Virus

38
Q

Symptoms of arbovirus

A

encephalitis

39
Q

Vector s of Arbovirus

A

Arthropods (nmosquitos)

40
Q

Togavirus morphology

A

Enveloped RNA virus pos sense

41
Q

Symptoms of rubella

A

postauricular, auricuulotemporal lymphadenopathy
maculopapular rash beginning on face, spreading downard present for 3 days
fever, fatigue,arthritis

42
Q

Transmission of rubella

A

Respiratory droplets

43
Q

Congenital Rubella Manifestations

A

PDA, congenital cataract, congenital deafness

Mental retardation, miocrocephaly, , blindness, jaundice
blueberry muffin rash

44
Q

Rubella vaccine type

A

Live attenuated

45
Q

HIV positive CD4 count needed before vaccination

A

CD4>200

46
Q

Coronavirus structure

A

Encapsulated RNA positive sense virus

47
Q

Shape of capsule of coronavirus

A

Helical

48
Q

Coronavirus example

A

Common cold, SARS, MERS, acute bronchitis

49
Q

HIV morphology

A

RNA single strand virus, enveloped, Diploid (2 RNA molecules for virion)

50
Q

HIV genes and function

A

gag , p24, RNA capsule

env gene - envelope of virus makes glycoprotein 41 (transmembrane) and 120 (outer glycoprotein)

pol gene - reverse transcriptase

51
Q

Cell which HIV imnitially infects

A

Macrophage and Helper T cells (CD4)

52
Q

Prodrome of HIV

A

Lymphadenopathy, fever, lasting for several weeks, self limiting

53
Q

Events on the latent period

A

HIV replicates in lymph nodes

54
Q

AIDS CD4 count cutoff

A

<200

55
Q

Malignancy caused bny HIV

A

Diffuse large B cell llymphomna

56
Q

Receptors ion cell whioch allow HIOV to enter CD4

A

CCR5, (early)CXCR4 (late)

57
Q

Diagnosis of HIV

A

Screening - Elisa

Confirmation - Western Blot

58
Q

Drug for HIV in pregnant patients

A

Zidovudine

PLE Microbiology (9 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions