Protozoa Flashcards
Mode of infection of Giardia
Fecal-oral transmission
Infective stage of Giardia
Cysts
Symptoms of Giardia
Foul smelling diarrhea
Steatorrhea
Trophozoite shape
Ventral Sucker, shield like shape
Trophozoitte mode of illness
Attach to intestine, nbut not invade
Diagnosis of Giardia
Stool O&P - trophozoites on stool
ELISA Stool antigen
Treatment of Giardia
Metronidazole
Transmission of Entamoeba Histolytica
Cysts from contaminated water
Anal sex
Trophozoite mode of action
Invade intestine, travel to liver, usually right lobe
Symptoms of Entamoeba histolytica
Liver abscess Intestinal amoebiasis (bloody diarrhea, ulcerations
Flask shaped ulcers accociated with
Entamoeba histolytica
Diagnostic of Entamoeba histolytica
Trophozoites with endocytosed RBC in stool
Cysts / trophozoites in stool
ELISA for antibodies
Treatment of Entamoeba histolytica
Metronidazole
Luminal agents for entamoeba histolitica, for cysts
Paramycin
Iodoquinol
Most common cause of Diarrhea in HIV patient
Cryptosporidium
Morphology of cryptosporidum
Unicelluilar acid fast
Transmission of cryptosporidium
Ingestion of Cysts
Cysts of cryptosporidium contain how many sporozoites
4
Infection method of cryptosporidium
Sporozoites attach to intestinal wall
Treatment of Cryptosporidiuym
Nitrozoxanide
Spiramycin
Location of toxoplasma
Intracellular
Populatuions at risk for Toxoplasma
Pregnant, immunocompromised
Infection transmission
Uncooked meat containing cysts
Oocytes in animal feces
Transplacental
Clinical manifestations of Toxoplasma
Brain abscess with ring enhancing lesions on CT/MRI
Encephalitis
Congenital: Chorioretinitis, Calcifications in brain, Hydrocephalus, Seizure
Deafness
Brain enceph from Toxoplasma mimics what
CNS lymphoma
Diagnosis of Toxoplasmna
Serology\
Biopsy with intramuscular cysts
Treatment of Toxoplasmosis
Sulfadiazine, Pyrimethamine
Prophylaxis given for immunocompromised begins at what CD4 count to prevent Toxoplasma
<100
Cotrimoxazole
African sleeping sickness is caused by
Trypanosoma brucei
Trypanosoma brucei vector is:
Tsetse fly
Clinical manifestations of African sleeping sickness
Coma
Cervical lymphadenopathy
Recurrent fever, undulating
Diagnosis of Trypanosoma brucei
Trypomastigotes on blood smear, lymph node, or spine CSF