Brainscape's Knowledge GenomeTM


Top Flashcards (Certified)
All Flashcards

PLE Microbiology > Fungi > Flashcards

Fungi Flashcards

1
Q

Fungus associated with bird or bat droppings, exposure to caves or chicken coops?

A

Histoplasma capsulatum

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Transmission of Histoplasma

A

Respiratory droplets,

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Histology/Diagnosis of Histoplasma

A

Macrophage with oval bodies, stained with KOH, Serum and Urine antigen tests

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Morophology of Histoplasma

A

Mold form - cold, in soil

Yeast form - hot, in body

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Symptoms of histoplasma

A

Mimics TB - Lung calcifications

Hepatosplemnomegaly with calcifictions

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Painful red nodules found in shin in Histoplasma infection

A

Erythema Nodosum

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Treatment of Histoplasma

A

Local - - azoles

Systemic infections - Amphotericin B

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Blastomycosis morphology

A

Yeast in body, mold in spores in soil

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Transmission of blastomycosis

A

Inhalaition of spores

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Reproduction of Blastomycosis

A

Budding of yeasts while in the body

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Histology ahnd diagnosis of Blastomycosis

A

Hazy infilrents inlungs, cannonball lesions

Large cells on microsicopy

Skin and bone infections

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Transmission of coccidiomuycosis

A

Inhalatin of arthroconidia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Morphology of coccidiomycosis

A

Mold outside the boidy, spherule with endospores inside the luings (larger than RBCS)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

San Joaquin Valley Fever is caused by

A

Coccidiomycosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Clinical features of coccidiomycosis

A

Fever, cough, arthralguia, clear xray or with cavities, nodules,erythema nodosum

Skin and lung disseminated infection, osteomyelitis, meningitis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Systemic infection fungal found in brazil

A

Paracoccidomycosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Pattern of paracoccidiomycosis

A

Yeast form in lungs (captains wheel)

mold form in the soil

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Clinical sympttomsof paracoccidiodomycosis

A

pneumonia, lymphadenopathy, granuloma in lungs mucocutaneous lesions

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Spaghetti and meatballs appearance on KOH chain is associated with

A

Malassezia furfur

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Pathogenesis of pityriasis versicolor

A

Lipid degradationl, destroying melanocytes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Layer of skin affected in malassezia furfur

A

Stratum corneum

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

Malassezia furfur septicemia is associated with which population

A

Immunocompromized, NICU patients on TPN (lipophilic)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

Treatment for malassezia

A

Seleniuum Sulfide

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

Three classes of dermatophytes

A

Trichophyton, epidermophyton, microsporuim

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Source of dermatophytes
Man to man contact, or from anymals
26
Confirmation of dermatophyte infection
Hyphae on KOH skin scraping | Wood's lamp
27
Oral antifungal for sever e dermatophyte infection
Griseofulvin
28
Treatmetn for regular dermatophyte infection
Azoles, terbinafine (for onychomycosis)
29
Sporothrix is usually gotten from
Rose thorn wounds, tree bark, plants
30
Morphology of sporothrix
Dimorphic, mold and cigar shaped yeast, with branching hyphae
31
Manidestation of Sporothrix infection
Introduced in wound, and ascending infection across lymphatics
32
Diagnosis of sporothrix on biopsy
Giant cells with cigar shaped yeast
33
Treatment of sporotrichosis
Itraconazole, KI solution
34
Most common cause of systemic mycosis
Candida albicans
35
Morphology of Candida
Dimorphic - Pseudohyphae yeast in cold, Hyphae (mold) in warm (37 deg) (germ tubes)
36
Lab findings in Candida
Catalase positive
37
Candida commonly contaminates what lab sample
Sputum
38
Clinical manifestation of candida infection
``` Diaper rash Oral candidiasis (immunocompormised or people using steroids) Scrapeable oral thrush Esophagiitis (in HIV with CD4<100) Vaginal candidiasis (pH less than 4) Endocarditis ```
39
Treatment for candida
Azole for mild, Amphotericin B for severe, disseminated infection Nystatin - oral candidiasis Capsofungin - disseminated drug resistant candida
40
Aspergillus lab finding
Catalase positive
41
Aspergillus flavus produeces what toxins? found in what plant?
Aflatoxin, peanut
42
Aflatoxin is associated with what illness
Hepatocellular carcinomna
43
Aspergillus morphology
Acute angle branching of hyphae, Septations
44
Transmission of Aspergillus
Forms Conidiophores whioch are inhaled by humans
45
Clinical Symptoms of aspergillus
Allergic Bronchopulmonary - Type I hypersensitivity - wheezing, fever, migratory pulmonary infiltrate Aspergilloma - fungus ball - gravity dependent Angioinvasive aspergillosis - in immunocompromised - disseminated
46
CT finding of CNS aspergillosis
Ring enhancing lesions
47
Aspergillosis Treatment
Less serious - Voriconazole, Surgical debridement Severe - Amphotericin B
48
Cryptococcus morphology
Heavily encapsulated with polysaccharide antigen
49
Transmission of Cryptococcus
Soil, pigeon droppings, then inhaled, settles in the lungs and spreads
50
Cryptococcus lab test
Urease positive
51
Clinical manifestations of cryptococcus
Pulmonary - cough, dyspnnea | Meningitis, fever
52
Diagnosis of cryptococcus
Saboraud agar Bronchopulmonary washings stained with mucicarmine red or methanamine silver stain Lumnbar tap stained with Indiaink, look for halos (capsule) Latex agglutination test
53
Gross pathology of brain in Cryptococcus
Soap bubble lesions in gray matter
54
Treatment of Cryptococcus
Amphotericin B, Flucytosine (intensive phase) | Fluconazole (maintenance phase)
55
Causes of Mucormycosis
Mucormycosis | Rhizopus
56
Rhizopus is found in what substance
Bread - it is a bread mold
57
Transmission of mucormycosis
Spore inhalation, proliferation on blood vessel wall, feeding on ketones and glucose, penetrate cribriform plate and enter skull
58
Morphology of mucrmycosis
Non septate hyphae, wide angle branching (9 degrees)
59
Clinical symptoms of mucormycosis
Black eschar on face and nose - necrosis of nasal cavity Brain abscess
60
Treatment of mucormycopsis
Surgical debridement | Amphotericin B
61
Transmission of Pneumocystis jiroveci
Airborne
62
CD4 count in Pneumocystis infection
<200
63
Xray appearance of Pneumocystis
Ground glass appearance if with diffuse interstitial pneumonia
64
Diagnosis of PCP
Bronchoalveolar lavage - methamine silver stain shows disc shaped yeasts
65
Prophylaxis of PCP in HIV patients
Cotrimoxazole
66
Treatment of PCP pneuimonia
Cotrimoxazole | Pentamidine - if with sulfa allergy

PLE Microbiology (9 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions