Viruses and Prions Flashcards
The biological entities known to each type of cell
Viruses and Prions
The origin
Introduction to Viruses
Alive
Active Virus
Dead
Inactive Virus
Uses of the Viruses
Agents of Disease
Genetic Makeup
Unique Properties
Acellular
No organelles
Either DNA or RNA
Nucleic Acids
Doesn’t multiply unless invading
Obligate Intracellular
The parts
The General Structure of Viruses
Than average Bacteria
Smaller
0.02 um
Parvoviruses
Than small Bacteria
Larger
450 um
Mimiviruses
Regular, repeating subunits trend
Molecular Structure
Only a piece of genetic material
A protein coat
Needed Structure
Protein Nucleic Acids
Capsids
Protein subunits forming the Capsids
Capsomeres
Only with Nucleocapsids
Naked Viruses
Fully formed Virus
Virion
Simple
Rod-shaped
Bonds together
Helical Caspids
Complex
Three-dimensional
Arranged together
Icosahedral Caspids
Essential attachment of the cells to host
Spikes
Genetic information carried by organism
Genome
RNA genomes for immediate translation
Positive-sense RNA
RNA genomes into proper forms
Negative-sense RNA
The special type of RNA
Retrovirus
Synthesizes DNA and RNA
Replicates RNA
Polymerases
HIV equipped DNA and RNA transcription
Reverse Transcriptase
Informal System
Animal / Bacteria / Plant
Envelope / Naked
DNA / RNA
Helical / Isocahedral
Formal System
Structure
Chemical Composition
Genetic Makeup Similarities
The classification of viruses
How Viruses Are Classified and Named
International Committee on the Taxonomy of Viruses
2020
Author
Orders’ ending
-Virales
Families’ end
-Viridae
Genera end
-Virus
The minute parasites
How Viruses Multiply
General Phases
Adsorption
Penetration
Uncoating
Synthesis
Assembly
Release
Attach
Virus encounters a point susceptible host cell
Adsorption
Tissue specificities
Tropism
Engulf
Host penetrates either the whole virus or the nucleic acid
Penetration
Dissolve
Viral nucleic acid into mended Cytoplasm
Uncoating
Entire virus engulfed
Endocytosis
Control
Make the new genomic materials and new proteins
Synthesis
Formation
From growing pool of parts
Assembly
Growth
Maturation in cell nucleus
Release
Curves virus component
Exocytosis
Invasive fit
Host Range
Human liver cells
Restricted Host Range
Primate intestinal and nerve cells
Moderately Restrictive Host Range
Mammal cells
Broad Host Range
Virus-induced damage
Cytopathic Effects
Compacted virus or damaged cell organelles
Inclusion Bodies
Fusion
Synctia
From few weeks to the remaining host’s life
Persistent Infections
Incorporating DNA into host
Provirus
Human cancers
Oncoviruses
Oncogenic effect
Transformation
Viruses infecting Bacteria
Bacteriophages
Intended disrupting effect
Lytic Phase
Special DNA phages
Temperate Phages
Inactive DNA phages
Prophage
Bacterial chromosome carrying Bacteriophage DNA
Lysogeny
Prophage activated and progressed
Induction
Bacteria acquired trait from Temperate Phages
Lysogenic Conversion
Transports bacterial genes from one Bacteria to another
Transduction
The hampered virologists
Techniques in Cultivating and Identifying Animal Viruses
Uses living embryos or animals
In Vivo Method
Uses laboratory cells or tissues
In Vitro Method
The viral infections
Viruses and Human Health
Difficult designs
Effective Therapies
Disrupting bacterial cells
Antibiotics
The chronic persistent diseases in humans and animals
Prions and Other Noncellular Infectious Agents
Agents of disease
Prions
Gradual degeneration and death
Creutzfeldt-Jakob Disease / CJD
Dependent on other viruses
Satellite Viruses
Parasitized viruslike agents
Viroids