Viruses Flashcards

1
Q

What can follow an HIV infection?

A

Opportunistic infections, which can lead to AIDS.

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2
Q

What kind of family is Zika? Drug therapy?

A

Favivirus. No drug therapy

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3
Q

What is the classification/genome structure of Influenza? Virus family?

A

RNA, Helical, Enveloped - ss segmented genome. Orthomyxo

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4
Q

What virus has a gapped genome?

A

Hep B

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5
Q

What is the composition of the 2016-17 influenza vaccine?

A

California, Hong Kong, Brisbane.

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6
Q

What is the shape of Icosohedral?

A

20 triangles, 30 edges, 12 vertices , and 2 3 and 5 fold axis of symmetry.

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7
Q

What are the TLRs and who contains them? What do they recognize?

A

3,7,8,9. Dendritic cells and macrophages. Recognize ds RNA

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8
Q

How do you decontaminate norovirus?

A

Use Clorox!

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9
Q

What HSVs are found in Oral cavity?

A

HSV-1, HSV-2, EBV, CMV.

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10
Q

The 1918 H1N1 pandemic by influenza was caused by the virus doing what?

A

Over stimulation of immune system, leading to over production of cytokines.

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11
Q

What is the difference between a physical particle vs virion?

A

Virion causes disease.

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12
Q

What are the 10 steps of viral replication?

A
  1. Attachment
  2. Penetration
  3. Uncoating
  4. Early transcription
  5. Early Translation
  6. DNA replication
  7. Late Transcription
  8. Late Transation
  9. Assembly
  10. Release
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13
Q

What viral families do Hep A, B and C come from?

A

A=Picorna
B= Hepaden
C= Flavivir

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14
Q

What is a primary infection of Herpes? Secondary?

A

Primary=Gingivostoatis and Whitlow

Secondary= Fever blisters.

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15
Q

What virus can cause oral papillomas or carcinomas?

A

HPV

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16
Q

What virus causes the common cold? Vaccine?

A

Rhinovirus. No vaccine because there are hundreds.

17
Q

What are the chances you will get HIV infection from saliva contact?

A

Very Low!

18
Q

What is an antigenic shift and what does it cause?

A

Genetic reassortment with H affected. Causes pandemic

19
Q

What is an antigenic drift and what does it cause?

A

Genetic mutation with H and N affected. Causes epidemic.