Host Pathogen Interaction

Question 1

define mutualism, Commensalism, Parasitism.

Answer 1

Mut= Both parties benefit
Com= one benefits, other is indifferent 
Par= one benefits, one is harmed.

Question 2

define 1.pathogenicity, 2.pathogen, 3.virulence

Answer 2

1. ability of organism to cause disease in a host
2. organisms able to cause disease in a host
3. degree of phthogenicity

Question 3

What are opportunistic pathogens?

Answer 3

Normal microbiota that can cause disease under certain circumstances.

Question 4

What are some examples of adhesions by pathogens?

Answer 4

Pili, receptor proteins, flagella and hooks, suction disks, harpoons, dextrans.

Question 5

What type of secretion systems in bacteria inject proteins directly into host cell?

Answer 5

Type III and Type IV

Question 6

What is the toxin activity for Diphtheria

Answer 6

Cytotoxin that kills cells in throat and builds up. Mechansism by using A-B toxin to inactivate elongation , preventing protein synthesis.

Question 7

What is the toxin activity for Cholera?

Answer 7

Enterotoxin causing diarrhea. Mechanism by A-B toxin increasing cAMP, releasing nutrients like NA+ and K+ from the cell.

Question 8

What is the toxin activity for Anthrax?

Answer 8

EF, LF, PA toxins cause increase in cAMP, localized edema, and death of target cell.

Question 9

What is the toxin activity for Botulism?

Answer 9

Neurotoxin A-B preventing acetylcholine release, resulting in flacid paralysis.

Question 10

What is the toxin activity for Tetanus?

Answer 10

Neurotoxin A-B decreasing chemical release from inhibitory neurons, resulting in spasms.

Question 11

What is the toxin activity for Shiga?

Answer 11

A-B toxin causing inhibition of protein synthesis, cell death.