Virus Flashcards

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1
Q

Who was one of the first people to discover viruses?

A

French-Canadian Felix D’Herelle

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2
Q

What are viruses?

A

Obligate intracellular parasites that have top infect a cell and use the host to make new copies of itself
-not living but can evolve

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3
Q

What was the first bacteria described?

A

Tobacco Mosaic virus

-only attacks plants even though we ingest it via smoking

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4
Q

What are viruses made of?

A

RNA (single or double stranded) and or DNA (double or single stranded)

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5
Q

How do viruses attach to receptors?

A

Glycoprotein spikes attach to receptor sites on host cells

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6
Q

What is reverse transcriptase ?

A

Transcription from RNA to DNA

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7
Q

What is the capsid?

A

The outside protein shell of the virus

-comes in many different shapes (simple and complex)

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8
Q

What is a bacteriophage?

A

The insect looking visor with a head, neck and legs

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9
Q

How do viruses get into their hots?

A

Need a natural opening, if not the virus will just remain on top doing nothing

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10
Q

What is a host range?

A

Viruses within the range of organisms they can affect but have viral specificity which refers to what cell types they can infect

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11
Q

What are bacteriophages and how to they infect bacteria?

A

Viruses that infect bacteria with releasing lysozyme to destroy they bacterial cell wall peptidoglycan

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12
Q

What is the process called in which a virus makes copies of itself in another host?

A

Replication

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13
Q

What are the 5 stages to virus replication?

A

Absorption- attaching to host

Penetration-virus enters cell

Synthesis-genes are transcribed direct the cost cell cytoplasm to make components of the evirus

Maturation- components assemble into complete virus copies

Release- new virus release which may or may not kill host cell

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14
Q

What is the lytic cycle?

A

Immediate infection, replication and exiting of cell

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15
Q

What is the lysogenic/provirus phase?

A

When virus is dormant in cells until triggered to replicate

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16
Q

What is the envelope?

A

Animal viruses possess an outer lipid membrane

17
Q

How are viruses released from animal cells?

A

Released via exocytosis which doesn’t kill the cell. Virus con retain a piece of the wall in their envelope and make it easier to defuse into another cell

18
Q

What are Naked animal viruses?

A

Do not have an envelope, they have many spikes of glycoprotein to recognize and bind to host cell receptors

19
Q

How do you defend against viral infections?

A

Immune system, also by activation of the immune system to recognize the virus prior to infection

20
Q

What are the 3 theories as to where viruses came from?

A
  1. Groups of genes that evolved and left the cell
  2. No tree of virus
  3. Early in evolution, virus was a little piece pf DNA or RNA that broke apart form cell division. They were complementary with the cell so it could get back in
21
Q

What is the central dogma?

A

DNA produces RNA and protein and DNA