Virulence Factors and Modes of Disease Transmission - Topic 2 Flashcards
What is virulence?
The ability of a pathogen to infect the host and cause a disease
What are virulence factors?
The tools used by microorganisms to be able to cause disease processes in the body
What is pathogenesis?
Pathogenesis is the process by which an infection leads to disease
How do adherence factors aid in pathogenesis?
Allowing pathogens to attach to host cells and tissues, which is crucial for colonization, evasion of the immune system, and the establishment of infection.
How do invasion factors aid in pathogenesis?
Enabling pathogens to penetrate host tissues, evade the immune response, and spread within the host, thereby facilitating infection and disease progression.
How do capsules aid in pathogenesis?
Protecting pathogens from phagocytosis by host immune cells, enhancing their ability to evade the immune system and establish infections.
How do toxins aid in pathogenesis?
Damaging host cells and disrupting functions, which enhances infection spread and severity.
How do lifecycle changes aid in pathogenesis?
By helping pathogens adapt, evade immunity, and enhance survival and transmission.