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Board Review - B - Microbiology > Virology IV > Flashcards

Virology IV Flashcards

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Biology 101 flashcards
1
Q

3 genes of HIV

A

structural

env - gp120 and gp41
gag - p24
pol - reverse transcriptase, aspartate protease, integrase

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2
Q

HIV reverse transcriptase

A

synthesize dsDNA from genomic RNA

dsDNA - integrated to host genome

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3
Q

HIV binding

A

gp120 - attachment to CD4+ cells

gp41 - transmembrane - fusion and entry to cell

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4
Q

capsid protein HIV

A

p24

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5
Q

coreceptor HIV binding

A

binds to CD4 - needs coreceptor

macros - CCR5 - early infection
T cells - CXCR4 - late infection

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6
Q

homozygous CCR5 mutation

A

immune HIV

heterozygote - slower course

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7
Q

diagnosis of HIV

A

ELISA - rule out test

western blot - rule in test

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8
Q

diagnosis of AIDS

A

CD4 less than 200

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9
Q

anti-gp120

A

cross placenta

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10
Q

infection in HIV positive - CD4 less than 500

A 
candida 
EBV
bartonella hencellae
HHV-8
cryptosporidium
HPV
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11
Q

HIV candida

A

CD4 less than 500

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12
Q

HIV EBV

A

CD4 less than 500

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13
Q

HIV bartonella henselae

A

CD4 less than 500

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14
Q

HIV HHV8

A

CD4 less than 500

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15
Q

HIV cryptosporidium

A

CD4 less than 500

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16
Q

HIV HPV

A

CD4 less than 500

17
Q

HIV CD4 less than 200

A

toxoplasma gondii
HIV
JC virus
pneumocystic jirovecii

18
Q

HIV toxoplasma gondii

A

CD4 less than 200

19
Q

HIV HIV infection

A

CD4 less than 200

20
Q

HIV JC virus

A

CD4 less than 200

21
Q

HIV pneumocystic jirovecii

A

CD4 less than 200

22
Q

HIV patient CD4 less than 100

A 
aspergillus
cryptococcus neoformans
candida albicans
CMV
EBV
histoplasma capsulatum
mycobacterium avium intracellulare
23
Q

HIV aspergillus

A

CD4 less than 100

24
Q

HIV cryptococcus neoformans

A

CD4 less than 100

25
Q

HIV candida albicans

A

CD4 less than 100

26
Q

HIV CMV

A

CD4 less than 100

27
Q

HIV EBV

A

CD4 less than 100

28
Q

HIV histoplasma capsulatum

A

CD4less than 100

29
Q

HIV myobacterium avium intracellulare

A

CD4 less than 100

30
Q

prion disease

A

alpha-helical protein - to beta-pleated form

PrP-C to PrP - SC

resistant to sterilizing procedures - including autoclave

31
Q

spongiform encephalopathy

A

prio disease

32
Q

creutzfeldt jakob disease

A

rapid progressive dementia
typically sporadic

prion disease

33
Q

bovine spongiform encephalitis

A

prion disease

aka mad cow disease

34
Q

kuru

A

acquired prion disease

cannibals - who eat brains

Board Review - B - Microbiology (16 decks)

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