Mycology I Flashcards

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1
Q

dimorphic fungi at temp

A

cold - mold
heat - yeast

except cocidiomycosis - spherule in tissue

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2
Q

tx for local mycosis infection

A

flucanozole

itraconazole

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3
Q

tx for systemic mycosis infection

A

amphotericin B

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4
Q

mississippi and ohio river valley, pneumonia, macrophage filled

A

histoplasmosis

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5
Q

histoplasmosis

A

mississippi and ohio river valley

fills macrophages

bird and bat poo

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6
Q

blastomycosis

A

east of mississippi river and central america

inflammatory lung disease - disseminate skin and bone

granuloma nodules form

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7
Q

coccidiomycosis

A

southwest US, Cali

pneumonia and meningitis

increased rate after earthquake - dust to air

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8
Q

spherule filled with endosores

A

coccidiomycosis

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9
Q

captains wheel formation

A

paracoccidiomycosis
in latin america

budding yeast

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10
Q

cutaneous mycosis

A

tinea

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11
Q

cutaneous fungal infection

A

dermatophyte

tinea

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12
Q

dermatophytes

A

cause tinea

microsporum, trichophyton, epidermophyton

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13
Q

microsporum

A

dermatophyte - cutaneous fungal infection

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14
Q

trichophyton

A

dermatophyte - cutaneous fungal infection

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15
Q

epiermophyton

A

dermatophyte - cutaneous fungal infection

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16
Q

tinea capitis

A

head/scalp fungal infection

dermatophyte

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17
Q

tinea corporis

A

body fungal infection

dermatophyte

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18
Q

tinea cruris

A

inguinal area fungal infection

dermatophyte

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19
Q

tinea pedis

A

foot fungal infection

3 varieties:
1 interdigital MC
2 mocassin
3 vesicular

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20
Q

tinea unguium

A

nailbed fungal infection

aka onychomycosis

21
Q

onychomycosis

A

nailbed fungal infection

tinea unguium

22
Q

tinea versicolor

A

from malassezia species

-yeast like fungus

23
Q

tinea versicolor path

A

degradation of lipid produces acids - damage melanocytes
-reults in hypopigmented and pink patches

often in summer and hot-humid weather

24
Q

spaghetti and meatballs on microscopy

A

tinea versicolor - malassezia

25
Q

oral thrush

A

candida in immunocompromised

26
Q

endocarditis in IV drug user

A

candida

27
Q

tx of candida

A

topical azole - vaginal
nystatin, flucanozole, or caspofungin - oral thrush
flucanozol, caspofungin, ampho B - systemic

28
Q

germ tube at 37C

A

candida albicans

29
Q

pseudohyphae and budding yeast at 20C

A

candida albicans

30
Q

septate hyphae branch at 45 egrees

A

aspergillus fumigatus

31
Q

aspergilloma

A

in lung cavity - after TB

32
Q

aflatoxins

A

produced by aspergillus species

-associated with hepatocellular carcinoma

33
Q

allergic bronchopulmonary aspergillosis

A

asthma and CF association

bronchiectasis and eosinophilia

34
Q

india ink stain with halos

A

cryptococcus neoformans

35
Q

cryptococcus neoformans

A

heavily capsuled yeast

-soil and pigeon droppings

36
Q

pigeon droppings

A

cryptococcus neoformans

37
Q

sabouraud agar

A

culture of cryptococcus neoformans

38
Q

soap bubble lesion in brain

A

cryptococcus neoformans

39
Q

mucormycosis

A

diabetic ketoacidosis

mucor and rhizopus specie

fungi proliferate blood vessel wall - penetrate cribriform plate - enter brain

rhinocerebral frontal lobe abscess

HA, facial pain, black necrotic eschar on face

40
Q

tx of mucormycosis

A

surgical debridement

amphotericin B

41
Q

pneumocystis pneumonia

A

diffuse interstitial pneumonia
-with pneumocystis jirovecii

get disease if immunosuppressed (ex/ AIDs)

42
Q

CXR for pneuomcystis pneumonia

A

B/L ground glass opacities

diagnosis - lung biopsy or lavage

43
Q

disc shaped yeast on methenamine sliver stain

A

pneumocystic jirovecii

44
Q

tx pneumocystis jirovecii

A

TMP-SMX
pentamide
dapsone (prophylaxis)
atovaquone (prophylaxis)

45
Q

prophylaxis in HIV for pneumocystis

A

dapsone and atovaquone

if CD4

46
Q

rose gardener gets pustule and ulcer along lymphatics

A

sporothrix schenckii

47
Q

sporothrix schenckii

A

dimorphic

cigar shaped budding yeast

48
Q

tx sporothrix

A

itraconazole

potassium iodide