Virology II Flashcards

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1
Q

genital herpes

A

HSV-2

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2
Q

neonatal herpes

A

HSV-2

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3
Q

chickenpox and shingles

A

HSV-3

varicella zoster

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4
Q

latent varicella zoster

A

in dorsal root or trigeminal ganglia

HSV-3

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5
Q

mononucleosis

A

EBV - HSV-4

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6
Q

mechanism of EBV infection

A

through CD21

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7
Q

monospot test

A

detect EBV

heterophile antibody

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8
Q

heterophile antibody

A

monospot test

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9
Q

burkitt lymphoma and nasopharyngeal carcinoma

A

EBV virus - HSV-4

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10
Q

mononucleosis with negative monospot

A

CMV

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11
Q

owl inclusion inclusion

A

CMV

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12
Q

roseola

A

HHV-6/7

seizure, diffuse macular rash

saliva transmission

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13
Q

tzanck test

A

detect multinucleated giant cells
-commonly seen in HSV-1,2,3

3 = VZV

also see intranuclear inclusions

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14
Q

reovirus

A

RNA virus
no envelope
DS linear
icosahedral double capsid

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15
Q

coltivirus and rotavirus

A

reoviruses

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16
Q

picornaviruses

A

ssRNA
linear positive strand
no envelope
icosahedral capsid

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17
Q

poliovirus

A

picornavirus

salk/sabin vaccines

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18
Q

rhinovirus

A

picornavirus

19
Q

coxsackievirus

A

picornavirus

20
Q

PERCH viruses

A

picornaviruses

poliovirus
echovirus
rhinovirus
coxsackievirus
hep A virus
21
Q

hepatitis A virus

A

picornavirus

22
Q

hep E virus

A

hepevirus

23
Q

hepevirus

A

ss positive RNA
no envelope
icosahedral

24
Q

hepatitis C virus

A

flavivirus

25
Q

yellow fever

A

flavivirus

26
Q

dengue

A

flavivirus

27
Q

west nile virus

A

flavivirus

28
Q

rubella

A

togavirus

29
Q

HIV

A

retrovirus

ss positive RNA
enveloped
complex and conical capsid

30
Q

common cold

A

coronavirus

ss postitive RNA

31
Q

influenza virus

A

orthomyxoviurs

32
Q

paramyxovirus

A

parainfluenza
RSV
measles
mumps

PRMM

33
Q

rabies

A

rhabdovirus

ss negative linear RNA virus
enveloped
helical capsid

34
Q

hepatitis D virus

A

delta virus

35
Q

norovirus

A

viral gastroenteritis

calcivirus

ss positive sense RNA

icosahedral capsid

36
Q

hep D

A

requires hep B

37
Q

negative strand viruses

A

need to transcribe to positive

virion brings its own RNA dependent RNA polymerase

arenavirus
bunyavirus
paramyxovirus
orthomyxovirus
arenavirus
reovirus
38
Q

runny nose

A

rhinovirus - nonenveloped RNA virus

picornavirus

> 100 serologic subtypes

acid labile - destroyed stomach acid

does not infect GI tract

39
Q

yellow fever

A

flavivirus

aedes mosquito

40
Q

high fever, black vomit, jaundice, councilman bodies, liver bx

A

yellow fever virus infection

41
Q

councilman bodies

A

eosinophilic apoptotic globules

42
Q

rotavirus

A

most important global cause of infantile gastroenteritis

segmented dsRNA virus

43
Q

influenza

A

negative sense ssRNA - 8 segment genome

orthomyxovirus

44
Q

flu shot

A

viral strain