Viral Pathology Flashcards

1
Q

Viral genome is made up of

A

DNA

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2
Q

Common to produce latent infections

A

Herpesviridae family

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3
Q

Small mouth ulcerations associated with fever and malaise

A

Primary herpetic gingivostomatis (primary lesion)

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4
Q

Lip ulceration

A

Herpes labialis

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5
Q

Type of herpes simplex virus found in oral cavity

A

Type I (CN V)

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6
Q

Lesions associated with type I herpes simplex virus (2)

A
Primary herpetic gingivostomatis (primary lesion)
Herpes labialis (secondary lesion)
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7
Q

Herpes simplex virus found in genitals and dormant to ______

A

Type II

Sacral ganglia

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8
Q

Varicella zoster virus is dormant in

A

Posterior root ganglia of spinal cord

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9
Q

Epstein barr virus is associated with (5)

A
Burkitt’s lymphoma
Infectious mononucleosis
Hodgkin’s lymphoma
Hairy leukoplakia
Nasopharyngeal carcinoma

BIHHN

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10
Q

Dse that has african endemic variant and B lymphocyte malignancy

A

Burkitt’s lymphoma

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11
Q

Dse transferred through saliva

A

Infection mononucleosis

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12
Q

Hodgkin’s lymphoma histologic appearance

A

Reed sternberg cells

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13
Q

White patches on tongue

A

Hairy leukoplakia

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14
Q

Carcinoma on the nasopharynx

A

Nasopharyngeal carcinoma

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15
Q

Causes of varicella zoster virus (2)

A

Chicken pox

Shingles

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16
Q

Human herpes virus 8

A

Kaposi’s sarcoma

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17
Q

One of the largest and most complex virus known

A

Smallpox/variola

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18
Q

Hx inclusion bodies of small pox

A

Guarneri bodies

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19
Q

Adenovirus causes (3)

A

Pharyngitis
Pneumonia
Conjunctivitis

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20
Q

Causes wart and cervical cancer

A

human papilloma virus

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21
Q

Smallest double stranded DNA virus

A

Hepadnavirus (hepa B virus)

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22
Q

Incubation period of hepa B

A

6-8 weeks

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23
Q

In hepa B it uses ______ that allows viral replication

A

Reverse transcriptase

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24
Q

Viral antigens of hepa B

A

HBsAg

HBcAg

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25
Q

Hepa B surface antigen

Detected in serum during blood test

A

HBsAg

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26
Q

Hepa B core antigen

A

HBcAg

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27
Q

Hepa B surface antibody

A

HBsAb

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28
Q

Only hepatitis virus that has DNA genome

A

Hepa B

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29
Q

Hepa that is parenteral and get through sexual contact

A

B
C
D

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30
Q

Hepatitis acquired fecal-oral

A

A

E

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31
Q

Virus of hepa A

A

Picornavirus

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32
Q

Virus of Hepa C

A

Flavivirus

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33
Q

Virus of Hepa D

A

Delta virus

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34
Q

Virus of hepa E

A

Calcivirus

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35
Q

Rabies virus
Hx intracytoplasmic bodies:______
Transmission:_______

A

Rhabdoviridae
Negri bodies
Rabid animal bite

36
Q

Picornaviruses (3)

A

Poliovirus
Rhinovirus
Coxsackie virus

37
Q

Virus that affects anterior horn of spinal cord - for motor

A

Poliovirus - poliomyelitis

38
Q

Transmission of poliovirus

A

Fecal to oral

39
Q

Ulcers in post of oral cavity

A

Herpangina

40
Q

Ulcers in oral cavity, hands and feet

A

Hand foot mouth dse

41
Q

Coxsackie A is associated with 2 dses

A

Herpangina

Hand fouth mouth dse

42
Q

Affects internal organs

A

Coxsackie B

43
Q

Types of paramyxoviruses (3)

A

Rubeola
RSV
Mumps

44
Q

Swelling of parotid gland (parotitis)

A

Mumps

45
Q

Associated with koplik spots

A

Rubeola

46
Q

Complication of mumps (2)

A

Orchitis

Oophoritis

47
Q

Togaviruses

A

Rubella or german measles

48
Q

Complication of rubella or german measles

A

Congenital defects (deafness or microcephaly)

49
Q

Most common cause of gastroenteritis in children

A

Rotavirus

50
Q

Attacks bone marrow cells resulting to leukopenia and thrombocytopenia

A

Dengue virus

51
Q

Capillary fragility test

A

Tourniquet test

52
Q

Virus that attacks liver resulting to yellowing of skin

Hx inclusion bodies :______

A

Yellow fever

Councilman bodies

53
Q

Virus causes microcephaly and encephalitis

A

Zika virus

54
Q

RetroVirus that causes AIDS

A

Lentivirus

55
Q

RNA blot test

A

Northern blot

56
Q

DNA blot test

A

Southern blot

57
Q

Detects HIV proteins

A

Western blot

58
Q

Common viral infections with maculopapular rash and blisters (4)

A

Smallpox
Chickenpox
Measles
Rubella

59
Q

Lesion containing pus

A

Pustules

60
Q

Elevated skin >1cm

<1 cm

A

Nodule

Papule

61
Q

Fluid filled lesion <5cm

> 5cm

A

Vesicle

Bullae

62
Q

Paramyxoviruses (3)

A

RSV

measles mumps

63
Q

Orthomyxovirus

A

Influenza

64
Q

Togavirus

A

Rubella

65
Q

Retrovirus

A

HIV

66
Q

Herpes virus (4)

A

Cytomegalovirus
Epstein barr virus
HSV 1
HSV 2

67
Q

Virus with kissing dse (2)

A

Epstein virus

Cytomegalovirus

68
Q

Hx appearance of cytomegalovirus

A

Owl’s eye

69
Q

Complication of shingles

A

Permanent paresthesia

70
Q

Other name of hepa B

A

Serum hepatitis

Dane particles

71
Q

Virus that uses reverse transcriptase (2)

A

Hepa B - if DNA

HIV - RNA

72
Q

Most difficult MO to be eliminated in sterilization (2)

A

Hepa B

Spore

73
Q

Incubation period of Hepa A

A

2-6 wks

74
Q

Bullet shaped virus

A

Rhabdoviridae

75
Q

2 dse associated with coxsackie A virus

A

Herpangiana

Hand foot mouth dse

76
Q

Herpangiana aka

A

Summer illness

77
Q

Influenza virus is in what family

A

Orthomyxovirus

78
Q

Tx for influenza virus

A

Amantadine

Rimantadine

79
Q

Rubeola aka

A

Measles

80
Q

Rubella aka

A

German measles

81
Q

Inflammation of testis

A

Orchitis

82
Q

Inflammation of ovary

A

Oophoritis

83
Q

Tx for mumps

A

None self limiting dse

84
Q

Vaccine for dead virus

A

Salk vaccine

85
Q

Vaccine for alive but weakened virus

A

Salbin (salba)

86
Q

Causes adult viral pneumonia and flu

A

Influenza virus

87
Q

Vector of flaviviruses

A

Aedes aegypti