Viral Pathology Flashcards by Carmina Tan

Viral genome is made up of

DNA

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Common to produce latent infections

Herpesviridae family

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Small mouth ulcerations associated with fever and malaise

Primary herpetic gingivostomatis (primary lesion)

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Lip ulceration

Herpes labialis

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Type of herpes simplex virus found in oral cavity

Type I (CN V)

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Lesions associated with type I herpes simplex virus (2)

Primary herpetic gingivostomatis (primary lesion)
Herpes labialis (secondary lesion)

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Herpes simplex virus found in genitals and dormant to ______

Type II

Sacral ganglia

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Varicella zoster virus is dormant in

Posterior root ganglia of spinal cord

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Epstein barr virus is associated with (5)

Burkitt’s lymphoma
Infectious mononucleosis
Hodgkin’s lymphoma
Hairy leukoplakia
Nasopharyngeal carcinoma

BIHHN

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Dse that has african endemic variant and B lymphocyte malignancy

Burkitt’s lymphoma

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Dse transferred through saliva

Infection mononucleosis

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Hodgkin’s lymphoma histologic appearance

Reed sternberg cells

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White patches on tongue

Hairy leukoplakia

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Carcinoma on the nasopharynx

Nasopharyngeal carcinoma

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Causes of varicella zoster virus (2)

Chicken pox

Shingles

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Human herpes virus 8

Kaposi’s sarcoma

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One of the largest and most complex virus known

Smallpox/variola

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Hx inclusion bodies of small pox

Guarneri bodies

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Adenovirus causes (3)

Pharyngitis
Pneumonia
Conjunctivitis

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Causes wart and cervical cancer

human papilloma virus

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Smallest double stranded DNA virus

Hepadnavirus (hepa B virus)

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Incubation period of hepa B

6-8 weeks

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In hepa B it uses ______ that allows viral replication

Reverse transcriptase

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Viral antigens of hepa B

HBsAg

HBcAg

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Hepa B surface antigen | Detected in serum during blood test

HBsAg

Hepa B core antigen

HBcAg

Hepa B surface antibody

HBsAb

Only hepatitis virus that has DNA genome

Hepa B

Hepa that is parenteral and get through sexual contact

B C D

Hepatitis acquired fecal-oral

A | E

Virus of hepa A

Picornavirus

Virus of Hepa C

Flavivirus

Virus of Hepa D

Delta virus

Virus of hepa E

Calcivirus

Rabies virus Hx intracytoplasmic bodies:______ Transmission:_______

Rhabdoviridae Negri bodies Rabid animal bite

Picornaviruses (3)

Poliovirus Rhinovirus Coxsackie virus

Virus that affects anterior horn of spinal cord - for motor

Poliovirus - poliomyelitis

Transmission of poliovirus

Fecal to oral

Ulcers in post of oral cavity

Herpangina

Ulcers in oral cavity, hands and feet

Hand foot mouth dse

Coxsackie A is associated with 2 dses

Herpangina | Hand fouth mouth dse

Affects internal organs

Coxsackie B

Types of paramyxoviruses (3)

Rubeola RSV Mumps

Swelling of parotid gland (parotitis)

Mumps

Associated with koplik spots

Rubeola

Complication of mumps (2)

Orchitis | Oophoritis

Togaviruses

Rubella or german measles

Complication of rubella or german measles

Congenital defects (deafness or microcephaly)

Most common cause of gastroenteritis in children

Rotavirus

Attacks bone marrow cells resulting to leukopenia and thrombocytopenia

Dengue virus

Capillary fragility test

Tourniquet test

Virus that attacks liver resulting to yellowing of skin | Hx inclusion bodies :______

Yellow fever Councilman bodies

Virus causes microcephaly and encephalitis

Zika virus

RetroVirus that causes AIDS

Lentivirus

RNA blot test

Northern blot

DNA blot test

Southern blot

Detects HIV proteins

Western blot

Common viral infections with maculopapular rash and blisters (4)

Smallpox Chickenpox Measles Rubella

Lesion containing pus

Pustules

Elevated skin >1cm <1 cm

Nodule Papule

Fluid filled lesion <5cm >5cm

Vesicle Bullae

Paramyxoviruses (3)

RSV | measles mumps

Orthomyxovirus

Influenza

Togavirus

Rubella

Retrovirus

HIV

Herpes virus (4)

Cytomegalovirus Epstein barr virus HSV 1 HSV 2

Virus with kissing dse (2)

Epstein virus | Cytomegalovirus

Hx appearance of cytomegalovirus

Owl’s eye

Complication of shingles

Permanent paresthesia

Other name of hepa B

Serum hepatitis | Dane particles

Virus that uses reverse transcriptase (2)

Hepa B - if DNA | HIV - RNA

Most difficult MO to be eliminated in sterilization (2)

Hepa B | Spore

Incubation period of Hepa A

2-6 wks

Bullet shaped virus

Rhabdoviridae

2 dse associated with coxsackie A virus

Herpangiana | Hand foot mouth dse

Herpangiana aka

Summer illness

Influenza virus is in what family

Orthomyxovirus

Tx for influenza virus

Amantadine | Rimantadine

Rubeola aka

Measles

Rubella aka

German measles

Inflammation of testis

Orchitis

Inflammation of ovary

Oophoritis

Tx for mumps

None self limiting dse

Vaccine for dead virus

Salk vaccine

Vaccine for alive but weakened virus

Salbin (salba)

Causes adult viral pneumonia and flu

Influenza virus

Vector of flaviviruses

Aedes aegypti