Viral Pathology Flashcards
Viral genome is made up of
DNA
Common to produce latent infections
Herpesviridae family
Small mouth ulcerations associated with fever and malaise
Primary herpetic gingivostomatis (primary lesion)
Lip ulceration
Herpes labialis
Type of herpes simplex virus found in oral cavity
Type I (CN V)
Lesions associated with type I herpes simplex virus (2)
Primary herpetic gingivostomatis (primary lesion) Herpes labialis (secondary lesion)
Herpes simplex virus found in genitals and dormant to ______
Type II
Sacral ganglia
Varicella zoster virus is dormant in
Posterior root ganglia of spinal cord
Epstein barr virus is associated with (5)
Burkittโs lymphoma Infectious mononucleosis Hodgkinโs lymphoma Hairy leukoplakia Nasopharyngeal carcinoma
BIHHN
Dse that has african endemic variant and B lymphocyte malignancy
Burkittโs lymphoma
Dse transferred through saliva
Infection mononucleosis
Hodgkinโs lymphoma histologic appearance
Reed sternberg cells
White patches on tongue
Hairy leukoplakia
Carcinoma on the nasopharynx
Nasopharyngeal carcinoma
Causes of varicella zoster virus (2)
Chicken pox
Shingles
Human herpes virus 8
Kaposiโs sarcoma
One of the largest and most complex virus known
Smallpox/variola
Hx inclusion bodies of small pox
Guarneri bodies
Adenovirus causes (3)
Pharyngitis
Pneumonia
Conjunctivitis
Causes wart and cervical cancer
human papilloma virus
Smallest double stranded DNA virus
Hepadnavirus (hepa B virus)
Incubation period of hepa B
6-8 weeks
In hepa B it uses ______ that allows viral replication
Reverse transcriptase
Viral antigens of hepa B
HBsAg
HBcAg
Hepa B surface antigen
Detected in serum during blood test
HBsAg
Hepa B core antigen
HBcAg
Hepa B surface antibody
HBsAb
Only hepatitis virus that has DNA genome
Hepa B
Hepa that is parenteral and get through sexual contact
B
C
D
Hepatitis acquired fecal-oral
A
E
Virus of hepa A
Picornavirus
Virus of Hepa C
Flavivirus
Virus of Hepa D
Delta virus
Virus of hepa E
Calcivirus
Rabies virus
Hx intracytoplasmic bodies:______
Transmission:_______
Rhabdoviridae
Negri bodies
Rabid animal bite
Picornaviruses (3)
Poliovirus
Rhinovirus
Coxsackie virus
Virus that affects anterior horn of spinal cord - for motor
Poliovirus - poliomyelitis
Transmission of poliovirus
Fecal to oral
Ulcers in post of oral cavity
Herpangina
Ulcers in oral cavity, hands and feet
Hand foot mouth dse
Coxsackie A is associated with 2 dses
Herpangina
Hand fouth mouth dse
Affects internal organs
Coxsackie B
Types of paramyxoviruses (3)
Rubeola
RSV
Mumps
Swelling of parotid gland (parotitis)
Mumps
Associated with koplik spots
Rubeola
Complication of mumps (2)
Orchitis
Oophoritis
Togaviruses
Rubella or german measles
Complication of rubella or german measles
Congenital defects (deafness or microcephaly)
Most common cause of gastroenteritis in children
Rotavirus
Attacks bone marrow cells resulting to leukopenia and thrombocytopenia
Dengue virus
Capillary fragility test
Tourniquet test
Virus that attacks liver resulting to yellowing of skin
Hx inclusion bodies :______
Yellow fever
Councilman bodies
Virus causes microcephaly and encephalitis
Zika virus
RetroVirus that causes AIDS
Lentivirus
RNA blot test
Northern blot
DNA blot test
Southern blot
Detects HIV proteins
Western blot
Common viral infections with maculopapular rash and blisters (4)
Smallpox
Chickenpox
Measles
Rubella
Lesion containing pus
Pustules
Elevated skin >1cm
<1 cm
Nodule
Papule
Fluid filled lesion <5cm
> 5cm
Vesicle
Bullae
Paramyxoviruses (3)
RSV
measles mumps
Orthomyxovirus
Influenza
Togavirus
Rubella
Retrovirus
HIV
Herpes virus (4)
Cytomegalovirus
Epstein barr virus
HSV 1
HSV 2
Virus with kissing dse (2)
Epstein virus
Cytomegalovirus
Hx appearance of cytomegalovirus
Owlโs eye
Complication of shingles
Permanent paresthesia
Other name of hepa B
Serum hepatitis
Dane particles
Virus that uses reverse transcriptase (2)
Hepa B - if DNA
HIV - RNA
Most difficult MO to be eliminated in sterilization (2)
Hepa B
Spore
Incubation period of Hepa A
2-6 wks
Bullet shaped virus
Rhabdoviridae
2 dse associated with coxsackie A virus
Herpangiana
Hand foot mouth dse
Herpangiana aka
Summer illness
Influenza virus is in what family
Orthomyxovirus
Tx for influenza virus
Amantadine
Rimantadine
Rubeola aka
Measles
Rubella aka
German measles
Inflammation of testis
Orchitis
Inflammation of ovary
Oophoritis
Tx for mumps
None self limiting dse
Vaccine for dead virus
Salk vaccine
Vaccine for alive but weakened virus
Salbin (salba)
Causes adult viral pneumonia and flu
Influenza virus
Vector of flaviviruses
Aedes aegypti