General pathology and Microbiology Flashcards
Inflammation indicates an ____ is present
Antigen
Cardinal signs of inflammation (5)
Rubor - redness Calor - heat Tumor - swelling Dolor -pain Functio laesa
Mediators of inflammation cause ____ and _____
Vasodilation
Inc vascular permeability
Mediators of Inflammation (4)
Prostaglandin
Bradykinin
Kallidin
Histamine
Most impt mediator of inflammation
Histamine
Mediator of inflammation that produces pain (3)
Prostaglandin
Bradykinin
Kallidin
Peripherally lining up of WBC
Preparation of diapedesis
Pavementing or migration
Specialized CD8
Natural killer cells
Exudates are seen in
Abscess
Transudate are seen in (2)
Edema
Gingival crevicular fluid
Passive movt of blood cells across endothelial wall
Diapedesis
Process of cell digestion (4)
Phagosome
Lysosome
Phagolysosome
Residual bodies
Cell eating
Phagocytosis
Matures in thymus
T lymphocytes
T helper cells
CD4
Cytotoxic T cells
CD8
*Dse deficient thymus (dec T cells) and PTH gland
DiGeorge Syndrome
Specialized CD8
NK cells
Matures in bone marrow
B lymphocytes
Activated B cells
Produces Ig
Plasma cells
Contains azurophilic granules
Neutrophils
Principal content of pus
Dead neutrophil
Vascular permeability with numerous proteins (albumin)
Example:_____
Exudate
Abscess
Vascular permeability with few proteins Seen in (2)
Transudate
Edema
Gingival crevicular fluid (GCF)
Specific gravity for
Exudate
Transudate
> 1.018
<1.012
Peripherally lining up of WBC
Pavementing or migration
Preparation for diapedesis
Pavementing or migration
Location of WBC
Central portion of blood
*Passive movt of blood cells across endothelial wall
Diapedesis
Specialized movt of lymphocytes across endothelium
Emperipolesis
Organelle used by WBC to move across endothelium
Pseudopods
*phenomenon through which blood borne antigens are attracted and fixed to areas of inflammation
Anachoresis
Once thereโs antigen, wbc from central portion will move
Peripheral
Cell eating
Phagocytosis
Process of cell digestion
Phagosome
Lysosome
Phagolysosome
Residual bodies
Injury > resistance what infection
Acute infection
Example of acute infection (2)
Ludwigโs angina
Cellulitis
Ludwigs angina bilateral involvement of (3)
Submandibular space
Sublingual spaces
Submental spaces
Inflammation of cells
More localized
AKA
Cellulitis
Phlegmon
Injury = resistance what infection
Chronic infection
Blade #____ for I and D
11
Blade #____ for Universal
15
Blade #____ for I distal incision
12
Blade #____ for Extraoral
10
Most common stage for chronic apical periodontitis
Granuloma
Lining of cyst
Stratified squamous
Leukocytosis is a characteristic of what infection
Acute bacterial infection
Lymphocytosis is a characteristic of what infection
Viral infection
Cells found in chronic infection (3)
Plasma cells
Lymphocytes
Macrophage
Type 1 hypersensitivity rxn
Mediator:
Example:(2)
Allergic
Anaphylactic
Immediate hypersensitivity
IgE
Asthma and urticaria
Type 2 hypersensitivity rxn
Mediator:
Example
Cytotoxic hypersensitivity
IgG
IgM
Hemolytic anemia
Erythroblastosis fetalis
Type 3 hypersensitivity rxn
Mediator:
Example
Immune Complex hypersensitivity Antigen and antibody complex SLE Serum sickness Arthus rxn
Type 4 hypersensitivity rxns
Takes days before reaction to appear
Mediator:
Delayed; T-cell mediated
Immune cells
DOC of low BP
Epinephrine 1:1,000
Stage of CAP
Abscess
Granuloma
Cyst
Types of immunity (2)
Non-specific/Passive/Innate
Specific/active/adaptive (lymphocyte)
Examples of passive immunity
Barriers - 1st line of defense
Phagocytes - 2nd
Mediator of Humoral immunity
B cells