Pharmacology II Flashcards
1
Q
Drugs with slight anticholinergic effects
A
DiTriBeAM
diophenhydramine Tricyclic antidepressants Benzodiazepines Antipsychotics Meperidine
2
Q
Gold standard of narcotics
A
Morphine
3
Q
Narcotics aka
A
Opioids
Opiates
Opium
4
Q
Morphine came from what plant
A
Poppy plant
Papaver somniferum
5
Q
Opioid receptors (4)
A
Limbic system
Area postrema
Solitary nuclei
Substansia gelatinosa of rolando
LASS
6
Q
Most common side effect of narcotics
A
Nausea
7
Q
Gate in gate control theory
A
Substansia gelatinosa of rolando
8
Q
Most accepted theory for pain
A
Gate control theory
9
Q
Opioid receptor responsible for nausea and vomiting
A
Area postrema
10
Q
Anti tussive drug
A
Dextromethorpan (rubitussin)
11
Q
Opioid receptor responsible for gag reflex cough reflex baroreceptor reflex chemoreceptor and gastric motility
A
Solitary nuclei
12
Q
Endogenous opioids produced by body (2)
A
Enhephalins
Endorphins
13
Q
Combination of Diphenoxylate and Atropine
A
Lomotic
14
Q
Laxative drug
A
Bisacodyl
15
Q
Drug for expectorant
A
Guaifenesin
16
Q
Narcotic agents block pain in PNS T or F
A
False
17
Q
Morphine triad
A
Miosis
Respi depression
Coma
18
Q
Components or drugs of neuroleptic analgesia
A
Neuroleptic agents or antipsychotics
Narcotics
Nitrous oxide
3N
19
Q
example of neuroleptic drug
A
butyrophenones
20
Q
Drug that causes dissociative anesth
A
Ketamine
21
Q
*drug that places px in trans like state
A
Ketamine
22
Q
Contraindicated drugs to glaucoma
A
Diazepam
Anticholinergic drugs!!!
(ditribeam)
23
Q
Other name of heroin
A
Diacetylmorphine
24
Q
Other name for acetaminophen
A
APAP
N-acetyl paraminophenol
25
Oxycodone + acetaminophen = ______
Tylox
26
Drug for orofacial pain
Codeine
27
Real anticholinergics ***
Belladona alkaloids
Atropine
Scopolamine
28
Dse Associated with px taking meth
Meth mouth
29
drug that shouldnt be combined with MAO inhibitors
MEPERIDINE
SSRI
Ephedrine
Epineph
30
Street name for heroin
Horse
Big H
Brown sugar
31
Street name for cocaine
Coke
| Candy
32
Street name for methamphetamine HCL
Crystals
Meth
Shabu
Poorman’s cocaine
33
Street name for marijuana
MJ
Weed
Blunt
Came from cannabis sativa
34
Oxycodone drug
Percocet
35
Route of administration
| Codeine, oxycodone, methadone
Oral
36
Morphine and meperidine route of administration
Parenteral (IV)
37
Narcotic antagonists (2)
Naloxone
| Naltrexone
38
Drugs with respiratory depression and dependence (4)
SNAB
Sedative hypnotics
Narcotics
Alcohol
Benzodiazepines
39
Impaired control over taking the drug
Psychic dependence
40
Continued administration of the drug is required to prevent unpleasant withdrawal syndrome
Physical dependence
41
Inhalation drugs
Halothane
| Desflurane
42
Blocks cox in CNS
Acetaminophen
43
Acetaminophen is ____ acting
Centrally acting non narcotic analgesic
44
Hepatotoxic drugs
Acetaminophen
Rifampicin
Tetracyclines
45
Narcotics metabolized to a CNS stimulant
Meperidine (Demerol) - NORmep
| Propoxyphene (Darvon)
46
Drugs with different classification from books opioids or non opioids
Tramadol
Propoxyphene (Darvon)
Petazocaine (Talwin)
47
Non scheduled narcotics
Tramadol
48
Drugs with neuroleptic anesthesia (3)
Narcotic
Butyrophenones (anti psychotic)
Nitrous oxide
49
Receptor of leukotrienes
Leukotriene receptor
50
If leukotrienes binds to receptor it will result to ______
Bronchoconstriction - reason for asthma
51
Prevent bronchoconstriction of leukotrienes
Leukotriene receptor blocker
52
Leukotriene receptor blocker drug
Montelukast
53
Both CNS and PNS have cyclooxygenase T or F
True
54
If arachidonic acid went to CNS there would be production of ____
CoX2 - produces prostaglandins
55
Effect of prostaglandin to CNS
Fever
| Pain
56
Cox 1 in PNS produces
Thromboxane A2 - formed by platelets
| Prostaglandins
57
Prostaglandin in cox 1 PNS effect
Inc renal blood flow
58
Cox 2 in PNS produces
Prostaglandins
| Prostacyclin
59
Effects of prostaglandin in cox 2 PNS
Pain
| Vasodilation
60
Effect of prostacyclin in cox 2 PNS
Vasodilation
61
3 end product of cyclooxygenase
Prostaglandin
Prostacyclin
Thromboxane a2
62
Non narcotics takes place to PNS except what drug
Acetaminophen
63
Drug that inhibit both COX 1 and 2 and is mainly peripherally acting
nsaids
64
Uses of non narcotic agents (3)
Anti pyretic
Analgesic
No inflam effect
65
Aspirin irreversibly block ____
Cox 1 in platelets
66
Aspirin and salicylates PNS or CNS
PNS
67
Prior to surgery, when should px stop taking aspirin
7 days
68
Reye’s syndrome
Child
Viral
Aspirin
69
Drug used to treat salicylism
Sodium bicarbonate
70
What parent drug is converted to acetaminophen
Phenacetin
71
Narcotic agents when excessive dose can lead to narcotic like adverse effects (2)
Pentazocaine
| Propoxyphene
72
Aspirin + NSAIDS can enhance (2)
Warfarin (Coumadin)
| Coumarin
73
NSAIDS drug uses (3)
Anti inflam
Analgesics
Mild anti pyretic
74
Which of the ffg drug should not be given if px will undergo surgery
NSAIDS (aspirin) PART OF NSAIDS PADIN
75
NSAID that selectively blocks COX 2
Cox 2 inhibitor
76
Only nsaid with no side effects
Cox 2 inhibitors
77
Type of non narcotic without anti inflam effect
Acetaminophen
78
Classification of aspirin (3)
Non narcotic
NSAID
salicylates
79
Drg uses of aspirin (4)
Anti pyretic
Analgesics
Mild anti inflam
Blood thinner
80
Overdose of aspirin
Salicylism
81
Cox 2 inhibitor drugs
Celecoxib
Etoricoxib
Valdecoxib
82
Ideal days for taking cox 2 inhibitor
7days
83
Cox 2 inhibitors reduces pain, fever, and inflammation without having GI problems T or F
True
84
Steroidal drugs suffix
- sone
| - lone
85
Corticosteroids rx
Bilateral mandibular radiolucencies
86
Steroidal drugs inhibits ____ resulting to dec arachidonic acid
Phospholipase a2
87
Steroidal drug uses
```
Anti inflam
Immunosuppressants
Prevents graft rejection
Prevents prosthetic rejection
Tx for addison dse
```
88
*before surgical extraction, what will do if px is under long term steroidal therapy
Increase dose or double the dose
89
Antipsychotic drugs aka (3)
Major tranquilizers
Neuroleptic agents
Hallucinogens
90
Dse with excessive dopamine levels
Schizophrenia
91
Dse with dec dopamine
Parkinson’s dse
92
Adverse effect of first gen antipsychotics
Extra pyramidal syndrome (tardive dyskinesia)
93
First gen antipsychotic drugs (3)
Phenothiazines - chlorpromazine
Butyrophenones - droperidol
Thioxanthenes
94
Second gen antipsychotic drug
Clozapine
95
Second gen has (4) receptor antagonist in limbic system
D1
D2
D4
D5
96
Bipolar disorder aka
Manic depression syndrome
97
DOC for manic depressive syndrome
Lithium ion
98
Antidepressant drug given to bipolar px
Tricyclic antidepressants
99
Most common TCA
Amitriptyline (si ami laging pinagttripan)
100
Drug given to px with tourettes
Antipsychotic drugs
101
Pharma effects of antipsychotics (5)
```
Reduction in psychosis
Emotion quieting
Dec convulsion
Sedation
Anticholinergic effect
```
102
Adverse effect of antipsych drugs
Tardive dyskinesia
Parkinsonism
Akathisia
103
Antipsychotic mainly d2 receptor antagonist
First gen antipsychotics
104
Antipsychotic drug with antihypertensive properties
Reserpine
105
Drugs for parkinsons dse (4)
L-dopa
Stimulants
MAO inhibitors
Anticholinergic drugs
106
Neuroleptic analgesia
A. Narcotics
B. Butyrophenones
C. N2O2
C
107
Which of the ffg drugs can be used to treat parkinsonism like symptoms
A. Anticholinergic
B. Narcotics
C. Antidepressants
A.
