Viral illness

Question 1

What is glandular fever?

Answer 1

Infectious mononucleosis caused by EBV from infection by saliva

Question 1

What is glandular fever?

Answer 1

Infectious mononucleosis caused by EBV from infection by saliva

Question 2

EBV in children vs teenagers

Answer 2

Most ppl infected as children - very few sympotms
More severe symptoms in young adults

Question 3

Symptoms of glandular fever

Answer 3

Fever, sore throat and fatigue, swollen face

Question 4

What happnes when take amoxicillin with mononucleosis?

Answer 4

Intensely itchy maculopaoular rash in repsonse to amoxicillin or cefalosporins

Question 5

Features of glandular fever

Answer 5

Fever
Sore throat
Fatigue
Lymphadenopathy - swollen lymoh nodse
Tonsilar enlargement
Splenomegaly + splenic rupture in rare cases

Question 6

What test for in glandular fever

Answer 6

Heterophile antibodies

Question 7

How long does it take for heterophile anitbodies to be produced in response to EBV

Answer 7

6 weeks

Question 8

What are heterophile antibodies

Answer 8

Multipurpose antibodies produced by the body in response to EBV

Question 9

How test for EBV

Answer 9

Monospit test - Heterophile antibodies react ot horse RBCs
Paul Bunnell test - uses sheep RBC

Question 10

When are tests for infectious mononucleosis unrelaibale

Answer 10

100% specific
Not everone with IM produces heterophile antibodies
Can take up to 6 weeks for ABs to be produced
ONly 70-80% sensitive

Question 10

When are tests for infectious mononucleosis unrelaibale

Answer 10

100% specific
Not everone with IM produces heterophile antibodies
Can take up to 6 weeks for ABs to be produced
ONly 70-80% sensitive

Question 11

What do EBV antibodies target

Answer 11

Viral capsid antigen

Question 12

What does IgM antibodies for EBV suggest

Answer 12

Rises eraly - acute infection

Question 13

What does IgG antibodies for EBV show

Answer 13

Persists after condition
Suggests immunity

Question 14

Management of glandular gever

Answer 14

acute ill 2-3 weeks, self limiting
Can leave with fatigue for several months once infection cleared

Question 15

Advice after glandular fever

Answer 15

Avoid alcohol = impairs ability live to process
Avoid contact sports = risk splenic rupture
Emergency surgery if this happens

Question 16

Complications with galndular fever

Answer 16

• Splenic rupture
• Glomerulonephritis
• Haemolytic anaemia
• Thrombocytopenia
• Chronic fatigue
  also ass w Burkitts lymphoma

Question 16

Complications with galndular fever

Answer 16

• Splenic rupture
• Glomerulonephritis
• Haemolytic anaemia
• Thrombocytopenia
• Chronic fatigue
  also ass w Burkitts lymphoma

Question 17

How is mumps spread

Answer 17

Respiratory droplets

Question 18

Incbation of mumps

Answer 18

14-25 dyas

Question 19

Prognosis mumps and management

Answer 19

Self limitng - 1 weeks
Supportive management
Treat complications as occur

Question 20

What happens in prodrome of glandular fever?

Answer 20

Fever
Muscle aches
Lethargy
Reduced appetite
Headache
Dry mouth

Question 21

What is a key feature of mumps?

Answer 21

Parotid gland, unilateral or bilateral
with ass pain

Question 22

Symptoms of complications galdnular fever

Answer 22

Abdominal pain = pancreatitis
Testicular pain + swelling - orchitis
Confusion, neck stiffness and headache (meningtis or encephalitis)

Question 23

Orchitis

Answer 23

Testicular inflammation

Question 24

What do in kawasakis

Answer 24

ECHo - check fro coarctation of the aorta

Question 25

How diagnose mumps?

Answer 25

PCR on saliva swab
Also tested for antibodies to mumps virus

Question 26

Management of mumps

Answer 26

Supportice, rest, fluids, analgesia
Self limiting
Notifiable disease

Question 27

Complciations of mumps

Answer 27

Pancreatitis
Orchitis
Meninigtis
Sensorineural hearing loss