Neonatal sepsis Flashcards
Common organsisms causing neonatal spesis
Group B strep
E.COLI
Listeria
Klebsiella
S.aureus
Risk factors
Vaginal GBS colonisation
GBS sepsis in prev baby
Maternal sepsis
Chorioamnionitis or fever >38 degrees
Prematurity (<37 weeks)
Early (premature) rupture of membrane
Pronlonged rupture of membranes
CLinical features of neonatal sepsi
- Fever
- Reduced tone and activity
- Poor feeding
- Respiratory distress or apnoea
- Vomiting
- Tachycardia or bradycardia
- Hypoxia
- Jaundice within 24 hours
- Seizures
- Hypoglycaemia
Red flags for sepssi
- Confirmed or suspected sepsis in the mother
- Signs of shock
- Seizures
- Term baby needing mechanical ventilation
- Respiratory distress starting more than 4 hours after birth
- Presumed sepsis in another baby in a multiple pregnancy
What do if find GBS found in vagina in pregnancy
Prophylactic antibiotics
What do when one risk factor or clinical features?
monitor the obs and clinical conditions for at least 12 hours
Two or more risk factors or clinical features of neonatal sepsis what do?
TREAT
When should antibiotics be started in neonatal suspected sepsis?
If SINGLE red flag
Two or more risk factors or clinical features
How quickly should antibiotics for neonatal sepsis be started?
within 1 hour
What need to do before starting antibiotics for neonatal sepsis?
Blood culutes
Baseline FBC and CRP
Lumbar puncture if features of menninfitis or infection strongly suspected or any CRP levels >10
What is the antibiotics of choice 1st line in neonatal sepsis?
Benzylpenicillin
Gentamycin
Cefotaxime - 3rd gen cephalosporun as alternative in low risk babaies
Why give cephalosporin in low risk babies?
Onoging management of neonatal sepsis?
Check CRP @ 24 hours
Check blood culture at 36 hours
Check CRP again at 5 days if still being treated
Onoging management of neonatal sepsis?
Check CRP @ 24 hours
Check blood culture at 36 hours
Check CRP again at 5 days if still being treated
When to stop antibiotics in neonatal sepsis?
Baby clinically well
blood cultures nefatvie after 36 hours
Both CRP results < 10
