Meningitis Flashcards

1
Q

What type of bacteria is neissiera meningitidis?

A

Gram negative diplococcus

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2
Q

What does meningococcal septicaemia cause?

A

Non blanching rash

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3
Q

What does the non blanching rahs in meningococcal septicaemia indicate the infection has caused?

A

Disseminated intravascular coagulopathy
SC haemorrhage

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4
Q

What is meningococcal meningitis

A

When bacteria is infecting meninges and CSF

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5
Q

Most common causes of meningitis

A

Neissiera meningitidis
Step pneumoniae
Neonates - group B strep

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6
Q

How is group B strep contracted?

A

During birth - normally in vaginal canal harmless

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7
Q

Presentation of meningitis

A

Fever
Neck stiff
Vomit
Headache
Photophobia
Altered consciousness
Seizures
Non blanching rash if septicaemia

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8
Q

How do neonates and babies present with meningitis?

A

Non specific signs and symptoms eg hypotonia
Poor feeding
Lethargy
Hypothermia
Bulging fontanelle

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9
Q

Who do NICE recommend LP for investgiation in?

A

Under 1 month with fever
1-3 months with fever and unwell
Under 1 year unexplained fever and other features of serious illlness

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10
Q

Special tests to perform for meningeal irritation

A

Kernigs test
Brudzinkis test

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11
Q

What is kernigs tets

A

involves lying the patient on their back, flexing one hip and knee to 90 degrees and then slowly straightening the knee whilst keeping the hip flexed at 90 degrees. This creates a slight stretch in the meninges. Where there is meningitis it will produce spinal pain or resistance to movement.

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12
Q

What is brudzinkis test

A

involves lying the patient flat on their back and gently using your hands to lift their head and neck off the bed and flex their chin to their chest. In a positive test this causes the patient to involuntarily flex their hips and knees.

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13
Q

Comunity treatment children with sus meningitis and non blacnhing rash

A

IM benzylpenicillin and hospital transfer
Dose is age dependent

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14
Q

What send for if meningococcal disease sus

A

LP
Meningococcal PCR

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15
Q

Antibiotics for children with meningitis under 3 onths vs over

A

Under 3 months - ceftriaxone + amoxicillin
Above 3 months - ceftriaxone
Vancomycin

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16
Q

What is amoxicillin given to cover?

A

Listeria

17
Q

Whn is vancomycin added to antibiotics for meningitits?

A

Risk of penicillin resistant pneumococcal infection eg recent travel or prolonged antibiotic exposure

18
Q

What are strerods used for in meninigitis? (bacterial)

A

Reduce frequency and severity of hearing loss and neurological damage

19
Q

Dosage of steroids given to children with meningitis

A

4 times daily for 4 days in children over 3 months IF LP -> bacterial meneigitnt

20
Q

What need to do if case of bacterial meningitis found>

A

Notifiable disease
Public heakth

21
Q

Who has highest risk of contracting meningitis after contact iwth patient

A

Contact 7 days prior to onset of illness

22
Q

Antibiotic choice for prophylaxis against meningitis

A

Single dose of ciprofloxacin
Given as soon as possible ideally within 24 horurs of initial diagnosis

23
Q

Common causes of viral meningitis

A

Herpes simplex virus
Enterovirus
Varicella zoster virus

24
Q

How to diagnose viral meningitis?

A

Lumbar puncture - send CSF for viral PCR

25
Q

How to treat HSV or VZV?

A

Aciclovir

26
Q

What is CSF tested for in meningitis?

A

Bacterial culture
Viral PCR
Cell count
Protein
Glucose

27
Q

What is CSF tested for in meningitis?

A

Bacterial culture
Viral PCR
Cell count
Protein
Glucose

28
Q

Which white cells are high inCSF in viral infection?

A

Lymphocytes
Bacterial - neutrophils

29
Q

What is protein and glucose levels in CSF in bacterial vs viral CSF?

A

Bacterial: protein - High. Glucose - low
Viral: protein normal or slightly raised. Glucose normal

30
Q

Complications of mennignitis

A

Haering loss
Seizures and epilepsy
Cognitive impairment and disability
Memory loss
Cerebral palsy - focal neurological deficits ef limb weakness or spasticity