viral hepatitis Flashcards

1
Q

causes

A

drug/alcohol induced
autoimmune
ischaemic

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2
Q

symptoms of acute hepatitis

A
fever
malaise
fatigue
nausea and vomiting
diarrhoea 
jaundice 
RUQ pain
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3
Q

Mallory’s hyaline bodies

A

alcoholic liver disease (acute hepatitis) and chronic active hepatitis

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4
Q

alpha feto protein

A

heptpcellular carcinoma

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5
Q

hepatitis A

A
RNA virus
faecal-oral spread
incubation 2-4 weeks 
fever, malaise and jaundice 
confirmed with presence of Hep A IgM
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6
Q

Hep A treatment

A

typically self-limiting
supportive
avoid alcohol
immunisation

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7
Q

Hepatitis B

A

DNA virus

BBB- blood, babies, B(sexual intercourse)

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8
Q

Hepatitis B complications

A

chronic hepatitis
hepatocellular carcinoma
fulminant liver failure

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9
Q

hep B management

A

antivirals (interferon alfa)

aim: clear Hep B surface antigen > causes cirrhosis

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10
Q

Hep B immunisation

A

given to children 2,3, and 4 months

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11
Q

Hep C

A

RNA

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12
Q

Hep C transmission

A

sexual intercourse

IVDU

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13
Q

Hep C symptoms

A

fatigue
85%- silent chronic infection
25%- cirrhosis > hepatocellular carcinoma
chronic hepatitis

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14
Q

Hep C investigations

A

anti-HCV= exposure
HCV-PCR test
liver biopsy

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