Peptic ulcer disease Flashcards
1
Q
cause
A
acid pepsin causes mucosal damage
2
Q
Aeitology
A
H.pylori infection- colonies mucous layer of stomach
NSAIDs
smoking, chemical irritants
3
Q
Symptoms
A
burning epigastric pain loss of appetite and weight feeling of fullness, nausea dyspepsia reflux symptoms haematemesis- ground coffee vomit
4
Q
investigations
A
H.pylori diagnosis
stool antigen, C13 urease breath test, serology (IgG)
endoscopy
5
Q
Treatment
A
PPI- omeprazole- of negative for H.pylori
H2 antagonists- ranitidine
antacids
H.pylori eradication therapy- 7 day course of PPI + amoxicillin + clarithromycin, or PPI + metronidazole + clarithromycin.
6
Q
eating improves the pain
A
duodenal ulcer
7
Q
eating worsens the pain
A
gastric ulcer
