Viral Hepatitis

Question 1

how do viruses attach to host cells

Answer 1

using receptor binding proteins

Question 2

what encloses the DNA or RNA of a virus

Answer 2

a virus encoded protein coat called a nucleocapsid
and sometimes a host cell membrane derived envelope

Question 3

symptoms of hepatitis

Answer 3

jaundice
dark urine
clay coloured stool
nausea and vomiting
loss of appetite
fever
abdominal pain
weakness

Question 4

which form of hepatitis has direct acting drugs

Answer 4

hep C

Question 5

are viruses with envelopes more or less sensitive to detergents and antibacterial wipes

Answer 5

more

Question 6

are faecal oral transmitted viruses more or less resistant than perenteral viruses

Answer 6

much more

Question 7

how are hep A-E transmitted

Answer 7

A and E - fecal oral
B, C and D - parenteral

Question 8

which hepatitis viruses cause chronic disease

Answer 8

B, C and D - often
A - never
E - only in transplant patients

Question 9

which hepatitis viruses are oncogenic

Answer 9

A - no
E - potentially
B and C - yes
D - unknown

Question 10

what age group mostly gets hep a

Answer 10

children and young adults

Question 11

how quickly does hep A onset

Answer 11

abruptly
commonly with pyrexia

Question 12

common reason for hep A disease

Answer 12

shellfish eaten raw or uncooked that have growth in contaminated water

Question 13

what % make a complete recovery from hep A

Answer 13

98%

Question 14

come age of hep B infection

Answer 14

babies and young adults

Question 15

transmission modes of hep B

Answer 15

mum-baby (vertical)
sexual

Question 16

how long does hep B virus last in body

Answer 16

for life
may reactive under immunosuppresion

Question 17

treatment for chronic hep B infection

Answer 17

interferon alpha or antivirals

Question 18

treatment for hep a

Answer 18

supportive

Question 19

where in the world is hep b most prevalent

Answer 19

south east asia
parts of china
sub-saharan african

Question 20

what % of babies/children infected with hep b go on to have chronic infection and how does this teens/adults

Answer 20

80-95% - children
5-10% - adults

Question 21

what age gets hep c

Answer 21

adults

Question 22

what is presentation of acute hep c infection

Answer 22

usually asymptomatic

Question 23

hep c treatment

Answer 23

interferon alpha and ribavirin
or
direct acting antivirals

Question 24

what is required for hep D replication

Answer 24

hep B

Question 25

hep e treatment

Answer 25

supportive
ribavirin for chronic infection

Question 26

viral causes of hepatitis

Answer 26

hep A-E
non-A/E hepatitis
epstein barr virus
cytomegalovirus
herpes simplex virus
rubella virus
enteroviruses
yellow fever virus