Functional GI Disorders Flashcards

1
Q

4 categories of functional GI disorders

A

functional dyspepsia
belching disorders
chronic nausea and vomiting disorders
rumination syndrome

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2
Q

what two syndromes come under functional dyspepsia

A

postprandial distress syndrome
epigastric pain syndrome

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3
Q

what is rumination syndrome

A

habit of regurgitating food which has already been digested

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4
Q

diagnostic criteria for functional dyspepsia

A

symptom onset more than 6 months ago
symptoms experienced for last 3 months

one or more of:
- bothersome postprandial fullness
- bothersome early satiety
- bothersome epigastric pain
- bothersome epigastric burning

and no evidence of structural disease that is likely to explain symptoms

structural disease must be ruled out with an endoscopy

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5
Q

what is post-prandial distress syndrome

A

type of functional dyspepsia

fullness and satiety but no pain
gastric dysmotility or abnormal accommodation

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6
Q

what is epigastric pain syndrome

A

type of functional dyspepsia

pain and burning due to visceral hypersensitivity

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7
Q

new onset of dyspepsia >55 is likely to be

A

oncogenic disease

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8
Q

epigastric pain syndrome is due to hypersensitivity which can be treated by

A

SSRIs

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9
Q

what nerve supplies parasympathetic to gut

A

vagus

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10
Q

what type of synapse is parasympathetic supply to gut

A

cholinergic

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11
Q

what type of synapse is sympathetic

A

adrenergic

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12
Q

diagnostic criteria for IBS

A

abdominal pain

and

2 of
- pain related to defaecation
- change in stool frequency
- change in stool form

symptoms over 6 months
weekly for last 3 months

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13
Q

feature of pathophysiology of IBS

A

visceral hypersensitivity

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14
Q

what are the 4 types of IBS

A

IBS-C (constipated)
IBS-M (mixed)
IBS-D (diarrhoea)
IBS-U (unclassified)

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15
Q

what bristol stool classification is IBS-C

A

1 and 2

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16
Q

what bristol stool classification is IBS-D

A

6 and 7

17
Q

what bristol stool classification is IBS-M

A

1 and 6

18
Q

what two symptoms cannot be attributed to IBS without further investigation and exclusion of more sinister causes

A

rectal bleeding
nocturnal diarrhoea

19
Q

what does onset of IBS often follow

A

gastroenteritis
e.g. campylobacter infection

20
Q

symptoms of IBS

A

bloating
abdo distension
post-prandial urgency
diarrhoea-constipation alternating
passing mucus
sensation of incomplete evacuation

21
Q

what conditions are associated with IBS

A

migraine
dyspepsia
dyspareunia
bladder problems
fibromyalgia
chronic fatigue

22
Q

red flags to suggest other diagnosis than IBS

A

weight loss
rectal bleeding
anaemia
thrombocytosis
persistent diarrhoea
new onset over 50
frequent nocturnal symptoms
FHx bowel cancer/IBD

23
Q

what dietary changes help some with IBS

A

low FODMAP
lactose restriction
wheat/gluten restriction

24
Q

what is medication based on for IBS

A

on predominant symptom

25
Q

third treatment option other than drugs and diet

A

CBT
psychological therapies
hypotherapy
relaxation therapy