Venous Thromosis Flashcards
1
Q
list the hereditary thrombophilias
A
Factor V Leiden Prothrombin 20210 mutation Antithrombin deficiency Protein C deficiency Protein S deficiency
2
Q
what is the pathogenesis of anti-phospholipid syndrome?
A
Antibodies lead to a conformational change in β2 glycoprotein 1 (a protein with unknown function in health) which leads to activation of both primary and secondary haemostasis and vessel wall abnormalities.
3
Q
what are antiphospholipid anti-bodies also known as?
A
Lupus anticoagulants
