Haemostasis Flashcards
1
Q
what happens in Primary and Secondary Haemostasis?
A
Formation of platelet plug
Formation of fibrin clot
2
Q
Name naturally occurring anti coagulants
A
anti-thrombin III- binds to clotting factors
Protein C and Protein S
3
Q
what is the cause of thrombophilia?
A
Deficiency of naturally occurring anticoagulants. May be hereditary
4
Q
What are the consequences of the failure of platelet plug formation?
A
Mucosal Bleeding; Retina, Conjunctiva, Mouth Stool, Menhorragia. Spontaneous Bruising and Purpura
5
Q
Describe the formation of a Fibrin Clot
A
See slide
6
Q
What screening tests measure clotting time
A
Prothrombin time- Extrinsic Pathway- TF/VIIa
Activated Partial Thromboblastin Time- XIII/IXa
