Haemostasis Tutorial Flashcards

1
Q

What are the causes of isolated raised APTT

A

factor XIII, XI, XI, XII deficiencies

Heparin

lupus anticoagulant

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2
Q

How would a VWF deficiency present

A

Mucausal bleeding and prolonged APTT

VWF binds to fractor VIII

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3
Q

why does severe liver disease affect both primary and secondary haemostasis?

A

Produces clotting factors

Back log through portal hypertension causes hypersplenism

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4
Q

How would you differentiate between DIC and severe liver injury?

A

Check for elevated D dimers

Should be sky high in DIC

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