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Haematology > Myeloma and other plasma cell disorders > Flashcards

Myeloma and other plasma cell disorders Flashcards

1
Q

what are the key histological features of plasma cells

A

Eccentric ‘clock face nucleus’ on H&E

Plentiful blue cytoplasm

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2
Q

how do you detect paraproteins?

A
  • Serum Electrophoresis
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3
Q

What are Bence Jones Proteins?

How are they detected?

A

immunoglobulin light chains

Detected by urine electrophoresis

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4
Q

what is the mnemonic used to remember how myeloma affects the body?

A

CRAB

Calcium- raised
Renal Failure
Anaemia
Bone pain/ lesions

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5
Q

what condition is characterized by a Characteristic IgM paraproteinaimea

A

Waldenstrom’s Macroglobulinaemia

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Haematology (23 decks)

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