Vasculitis viruses Flashcards
how many general vasculitis inducing viral classes are there
5 groups: adeno, equarte, orbi, pesti, malig catarrhal
equartevirus strand type and special characteristics
SS RNA, infects macrophages, PI animals
where do all arteriviruses infect
macrophages
herd of horses with edema, hemorrhage, fever, nasal discharge. #1 ddx
EVA (equartevirus)
what are our three orbiviruses
blue tongue, african horse sickness virus and epizootic hemorrhagic diesase
orbivirus characteristics and strand type
DS RNA. arthropod-borne, causes seasonal spikes of infection, noncontagious
what species get blue tongue
sheep, and some cattle and goats
what are the signs of vasculitis viruses
edema and hemorrhage: localized, petechial or systemic, fever.
which syndrome of african horse sickness keeps transmission going
mild subclinical form in zebras and donkeys
what are the two major diseases of WTD in the US
epizootic hemorrhagic diesease (orbi) and adenovirus. look exactly the same. test for ddx
key features of pestiviruses
SS RNA. PI animals main source of virus. repro issues if dam infected
what causes a PI pig causing petechial hemorrhage, an infarcts
classical swine fever
transmission of hog cholera (classical swine fever, pesti)
uncooked swill, PI animals
what is the only DNA virus that is arthropod vector transmission
african swine fever
what is the main pathology for african swine fever?
cytokine storm and hemorrhage due to DIC. apoptosis of macros, monocytes and lmpyhocytes
unique features about malignant catarrhal fever transmission
reservoir hosts (sheep) do not have clinical disease and cow-cow transmission does not occur
what are the unique signs of malignant catarrhal fever in cattle
corneal edema, neuro signs, GIT hemorrhage
what does the coggins test test for
equine infectious anemia (lentivirus)
what is the most important transmission of Eq infectious anemia
flies.
what is key for all lentiviruses
the lenti are for lifey
equine with rucurrent bouts of fever, anemia, weight loss, edema, petechia
think equine infectious anemia (lenti)
what is the most appropriate/common treatment for equine infectious anemia
complete isolation >200 yards away from other equine or euthanasia as QOL is significantly decreased in the herd animal
what is classical swine fever
pestivirus, necrotizing tonsilitis
