Vasculitides

Question 1

Weak pulses in the upper extremities

Answer 1

Takayasu arteritis

Question 2

Granulomas of lung, glomerulonephritis, c-ANCA positive

Answer 2

Granulomatosis with polyangitis

Question 3

Necrotizing immune complex inflammation of visceral/renal vessels

Answer 3

Polyarteritis nodosa

Question 4

2-year-old East Asian female

Answer 4

Kawasaki disease

Question 5

20-year-old East Asian female

Answer 5

Takayasu arteritis

Question 6

Young male smoker

Answer 6

Thromboangiitis obliterans

Question 7

Young asthmatics

Answer 7

Eosinophilic granulomatosis with polyarteritis

Question 8

infants and young children, involves the coronary arteries

Answer 8

Kawasaki disease

Question 9

Most common vasculitis

Answer 9

Giant cell arteritis (temporal arteritis)

Question 10

Associated with Hep B infection

Answer 10

Polyarteritis nodosa

Question 11

Occlusion of opthalmic artery can lead to blindness

Answer 11

Giant cell arteritis (temporal arteritis)

Question 12

Perforation of nasal septum

Answer 12

Granulomatosis with polyangitis

Question 13

Unilateral headache, jaw claudication

Answer 13

Giant cell arteritis (temporal)

Question 14

c-ANCA positive

Answer 14

Granulomatosis with polyangitis

Question 15

p-ANCA positive

Answer 15

Eosinophilic Granulomatosis with polyangitis (Churg-Strauss), microscopic polyangitis

Question 16

Treatment for thromboangiitis obliterans

Answer 16

smoking cessation

Question 17

Treatment for giant cell arteritis

Answer 17

high dose steroids

Question 18

Associated with polymyalgia rheumatica (joint pain in shoulders, neck, hip girdle)

Answer 18

Giant cell arteritis

Question 19

increased ESR

Answer 19

Giant cell arteritis

Question 20

Granulomatous thickening and narrowing of aortic arch and proximal great vessels

Answer 20

Takayasu arteritis

Question 21

immune complex mediated vasculitis involving the renal and visceral vessels, negative ANCA

Answer 21

polyarteritis nodosa

Question 22

Signs and symptoms of Kawasaki disease

Answer 22

CRASH and burn - Conjunctival injection, Rash (polymorphous –> desquamating), Adenopathy (cervical), Strawberry tongue, Hand-foot changes (edema, erythema)
burn = Fever (always present)

Question 23

Tx for Kawasaki disease

Answer 23

IV IG and aspirin

Question 24

Triad of Granulomatosis with Polyangitis

Answer 24

Focal necrotizing vasculitis
Necrotizing granulomas in the lung and upper airway
Necrotizing glomerulonephritis

Question 25

Tx of Granulomatosis with Polyangitis

Answer 25

cyclophosphamide, corticosteroids

Question 26

Asthma, sinusitis, skin nodules or purpura, peripheral neuropathy (wrist/foot drop)

Answer 26

Eosinophilic granulomatosis with polyangitis (Churg-Strauss)

Question 27

Triad of Henoch-Schonlein purpura

Answer 27

palpable purpura on buttocks and legs
arthalgias
abdominal pain

Question 28

Vasculitis secondary to IgA IC deposition

Answer 28

Henoch-Schonlein purpura

Question 29

Most common childhood vasculitis, usually follows URI

Answer 29

Henoch-Schonlein purpura