Autoantibodies Flashcards by Alexis Quade

Q

anti-IgG antibodies

A

Rheumatoid arthritis

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Q

Anti-citrullinated protein antibodies (ACPA)

A

Rheumatoid arthritis

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Q

Antinuclear antibodies (ANA)

A

Systemic lupus erythematosus

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Q

Anti-Smith

A

Systemic lupus erythematosus

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Q

Anti-dsDNA

A

SLE - renal disease

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Q

Anti-histone

A

drug-induced lupus

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Q

Anti-centromere

A

CREST scleroderma

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Q

Anti-Scl-70 (anti-DNA topoisomerase)

A

Diffuse scleroderma

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Q

Anti-Jo-1

A

Polymyositis/Dermatomyositis

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Q

Anti-SSA (anti-Ro)

A

Sjogren syndrome

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Q

Anti-SSB (anti-La)

A

Sjogren syndrome

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Q

Anti-U1-RNP

A

Mixed connective tissue disease

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Q

Anti-desmoglein

A

Pemphigus vulgaris

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Q

Anti-acetylcholine receptor

A

Myasthenia gravis

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Q

Anti-endomysial (anti-tissue transglutaminase)

A

Celiac disease

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Q

Anti-gliadin

A

Celiac disease

Q

Anti-mitochondrial

A

Primary Biliary cirrhosis

Q

Anti-smooth muscle

A

Autoimmune hepatitis

Q

Anti-glutamate decarboxylase

A

Type 1 Diabetes Mellitus

Q

Anti-thyrotropin receptor

A

Graves disease

Q

Anti-thyroid peroxidase (anti-TPO)

A

Hashimoto’s thyroidits

Q

Anti-thyroglobulin

A

Hashimoto’s, Graves disease

Q

Anti-basement membrane

A

Goodpasture’s syndrome

Q

c-ANCA

A

Granulomatosis with polyangiitis

Q

p-ANCA

A

Pauci-immune crescentic glomerulonephritis
Churg-Strauss syndrome
Microscopic polyangiitis

Q

Anti-hemidesmosome

A

bullous pemphigoid

Q

Type 1 autoimmune hepatitis

A

ANA, anti-smooth muscle antibody

Q

Type 2 autoimmune hepatitis

A

anti-liver-kidney microsomal antibody, anti-liver cytosol antibody