Various Anaerobes Flashcards
1
Q
Physical description of these
A
- infections are always mixed
- all prefer to live at low redox potential; less O2
2
Q
Description of low redox potential
A
- low redox potential generated by facultative organisms like E. coli
- toxin O2 forms and their removal
- none have cytochromes, thus no ETC
- no respiration
3
Q
Description of bacteroides fragilis
A
- colon bacterium
- G negative
4
Q
Virulence factors of B. fragilis
A
- antiphagocytic capsule
- can produce some SOD and CAT, so not as badly affected by O2
- extracellular enzymes; neuraminidase and heparinase
- LPS not as toxic; abdominal abscess
5
Q
Description of prevotella melaninogenica
A
- oral coccobacillus
- G negative
6
Q
Virulence factor of P. melaninogenica
A
- collagenase
- found with others in brain and lung abscesses
7
Q
Description of Porphyromonas gingivalis
A
- oral rod
- G negative
8
Q
Infections by P. gingivalis
A
- implicated in gingivitis
- oral abscesses
- infections of warm, moist areas(axilla, groin, perineum)
9
Q
Description of Fusobacterium
A
- oral and colonic fusiform
- G negative
- usually in mixed infections
- infections monoculture in osteomyelitis
10
Q
Description of Peptostreptococcus
A
- colonic coccus
- G positive
- mixed infections of blood, bacteremia, and pleura/lungs
11
Q
Propionibacterium acnes
A
- epidermal pleomorphic
- G positive rod
- acne, possibly in brain abscesses
12
Q
Read this section in the notes
A
READ or at least skim the charts displayed in this packet
13
Q
Pathogenesis of Peptostreptococcus
A
- normal flora enter unprotected area via trauma
- anaeroboisis exists or is generated by facultative coinfecting organisms
- production of tissue destructive enzymes causes abscesses
- abdominal, salpingitis, lung/URT, brain
14
Q
Control of peptostreptococcus
A
- drainage of accumulated fluid
- Pencillin G if not bacteroids or prevotella
- Ceph 3 for brain abscesses
- metranidazole and clindamycin
