Pasteurella multocida Flashcards
1
Q
Physical description of pasteurella
A
- G negative
- coccobacilli
- facultative anaerobe
- 4 capsular antigens types
2
Q
Clinical presentation of pasteurella
A
- local or disseminated edematous soft tissue abscess
- rapidly progressive cellulitis
- following animal bite
- fowl; pneumonia
- cattle; fever
- rabbits; snuffles to hemorrhagic pneumonia
3
Q
Epidemiology of pasteurella
A
- almost always spread to humans by animal bites
- spread by fomites
4
Q
Pathogenesis of pasteurella
A
- antiphagocytic capsule
- pili, adhesion proteins, Fe binding proteins
- adheres to M phages but not engulfed
- growth in vivo as fast as in vitro
- growth and abscess formation is pathogenesis
5
Q
Control of pasteurella
A
- pen/amp. or ceph + tetracycline
- most animal bite infections are polymicrobial
