Mycoplasma Flashcards
1
Q
Physical description of mycoplasma
A
-exceedingly small
2
Q
Cell wall of mycoplasma
A
- no cell wall, membrane only
- membrane has sterols, require sterols to grow, obtains from host
- grows slowly on agar as tiny colonies with centers depressed
3
Q
Clinical presentation of mycoplasma
A
- Mild walking atypical pneumonia or tracheobronchitis
- insidious onset
- mild fever and non productive cough
- may become severe
- resolves in around 4 weeks - occasional myringitis, eardrum
- trigger for autoimmune encephalomyelitis
4
Q
Go to packet to review these slides, includes tables with description of sound noises
A
Got to mycoplasma packet
5
Q
Epidemiology of mycoplasma
A
- transmitted via respiratory droplets
- common in school age children
- higher incidence in winter
6
Q
Pathogenesis of mycoplasma
A
- proline rich adhesion protein
- when in host, elongated tip
- adheres to epithelial cells
- protein M covers up Ab Fab region, blocks Ab/Ag interact.
7
Q
Cytotoxic effects of mycoplasma
A
- production of H2O2, O2 radical
- competition for nutrients
- NOT intracellular
8
Q
Control of mycoplasma
A
- often don’t treat if mild
- tetracycline, erythromycin
- NO PENICILLINS
9
Q
Description of M. genitalium
A
- part of normal adult flora
- urethral and genital infections
10
Q
Description of M. hominis
A
- found in 10% of salpingitis cases
- also post part fever
11
Q
Description of Ureaplasma urealyticum
A
- requires 10% urea to grow - produces urease
- nongonococcal urethritis in males(bladder stones
- most common NGU is chlamydia trachomatis
