Variation in Lab tetsing Flashcards

1
Q

Physiological state changes may result in…

A

abnormal lab tests

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2
Q

Meals stimulate the production of…

A

Gastric acid

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3
Q

What happens to HCl, pH, and plasma chloride concentration when you eat?

A
  • Decrease HCl
  • Increases pH
  • Decrease plasma Cl
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4
Q

What does glucose absorption do?

A
  • Stimluates the release of insulin
  • Insulin causes the uptake of K into cells
  • Decreasing plasma K levels (hypokalemia)
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5
Q

Non-fasting samples may result in _____ test results?

A

Abnormal

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6
Q

When are the most reproducible test results obtained?

A

When the patient is fasting for 8-12 hours

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7
Q

What effects does stress have on test results?

A

Stress increases your BV, and then increased your BP

-Increased BV causes a dilution of plasma proteins

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8
Q

As a clinician, what should you do if your patient is under stress?

A

Don’t order elective testing if your patient is under stress

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9
Q

Describe the effects of exercising

A

Patients who exercise regularly have increased levels of plasma enzymes

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10
Q

What are examples of plasma enzymes?

A
  • Creatinine kinase
  • Asparate aminotransferase
  • Lactate dehydrogenase
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11
Q

Where are plasma enzymes found?

A

The liver

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12
Q

What are high levels of plasma enzymes often confused with?

A

Liver disease

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13
Q

Describe cyclic variation

A

Reproducible patterns of alteration in physiologic state that occur at specific days, months, or year

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14
Q

What is an example of cyclic variation?

A

Pituitary hormones

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15
Q

What type of variation do pituitary hormones demonstrate?

A

Ultradian variation

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16
Q

Define Ultradian variation

A

Variation occurring in less than a day

17
Q

How are pituitary hormones released?

A

Episodic bursts (results in periods of peaks and valleys)

18
Q

Example of cyclic variation

A

Cholesterol is 25% higher during the 2nd half of the menstrual cycle

19
Q

What effect do diaretics have?

A

They pull of fluid, sodium, and potassium

20
Q

What happens when a patient is in an upright position?

A
  • Water and electrolytes are lost from the vascular space

- Proteins and protein bound substances become very concentrated

21
Q

What happens when you go from a sitting to a supine position?

A

Water and electrolytes move back into the vascular space

-Reduces the concentration of proteins by 10-15%

22
Q

What happens if you have high venous pressure?

A
  • The return of water and electrolytes to venous blood is impaired
  • This increases the concentration of proteins and protein bound substances
23
Q

How much does concentration increase after 3-5 minutes of tourniquet time?

A

5%

24
Q

How much does concentration increase after 10-15 minutes of tourniquet time?

A

15%

25
Q

As venous pressure remains high, circulation of fresh blood ______

A

Decreases

26
Q

What happens when the circulation of fresh blood decreases?

A

The cells continue metabolizing and the glucose decreases and lactate increases

27
Q

What does increased lactate result in?

A

Acidosis

28
Q

What does acidosis do to potassium?

A

Leads to leakage of K from cells, and elevates serum K levels

29
Q

What happens when you clench your fists?

A

Accelerates the rate that metabolic changes occur

-Increases serum K by 1-1.5 mmol/L in 1 minute

30
Q

If a patient has an IV, where do you take the blood sample from?

A

-Below where the IV is placed

31
Q

What color is the tube for… CBC?

A

Lavender

32
Q

What color is the tube for… metabolic panels

A

Red

33
Q

What color is the tube for… lipid profiles

A

red

34
Q

What color is the tube for…Thyroid function tests

A

red

35
Q

What color is the tube for… coagulation studies

A

blue