UW revision STATINS Flashcards
ASCVD = atherosclerotic cardiovascular disease.
how can be calculated risk?
Using Pooled Cohort Equations risk calculator
Pooled Cohort Equations risk calculator involves what measures?
age, sex, ethnicity, total cholesterol, HDL, diabetes status, smoking status, blood pressure
Pooled Cohort Equations risk calculator estimates what?
ESTIMATEs 10-year risk of ASCVD = atherosclerotic cardiovascular disease.
Indications for statin therapy. PRIMARY PREVENTION. LDL level?
LDL>= 190 mg/dl
Indications for statin therapy. PRIMARY PREVENTION. age and DM?
Age >= 40 + DM
Indications for statin therapy. PRIMARY PREVENTION. Estimated risk ASCVD?
Estimated 10-year risk of ASCVD > 7,5 - 10 proc.
Indications for statin therapy. SECONDARY PREVENTION. ALREADY ESTABLISHED ASCVD. what includes? 4
Acute coronary disease
Stable angina
Arterial revascularization (eg CABG)
Stroke, TIA, PAD
LDL alone is not used to guide the initiation of statin therapy, unless level of LDL is >= 190 mg/dl
.
What need to recommend to all regardless of statin therapy?
Healthy lifestyle for all.
If ASVCD < 7,5 proc?
Lifestyle changes and no statin
Hypothyroidism + statins can have stronger effect on myalgias. Some experts recommend to check TSH prior giving statin
.