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STEP 2 Cardio + Renal > UW revision amiodarone > Flashcards

UW revision amiodarone Flashcards

1
Q

Amiodarone. xray findings?

A

localized or diffuse reticular or ground-glass opacities.

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2
Q

Amiodarone. Pulmonary symptoms?

A

progressive dyspnea, nonproductive cough, bilateral inspiratory crackles, chest x ray findings.

INTERSTITIAL PNEUMONITIS - chronic, occurs months within start of use

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3
Q

Amiodarone. PFT findings?

A

Restrictive pattern, decr. DLCO

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4
Q

Amiodarone table. Cardiac?

A

Bradycardia, QT prolongation

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5
Q

Amiodarone table. Pulmonary?

A

Interstitial pneumonitis
Organizing pneumonia, lung nodules

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6
Q

Amiodarone table. Endocrin?

A

hypo or hyper thyroidism

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7
Q

Amiodarone table. Hepatic?

A

Hepatitis

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8
Q

Amiodarone table. Ophthalmic?

A

Corneal microdeposits
Optic neuritis

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9
Q

Amiodarone table. Dermatologic?

A

Blue-gray skin discoloration

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10
Q

Amiodarone table. Neurologic?

A

Peripheral neuropathy

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11
Q

Amiodarone pulmonary vs viral?

A

viral = fever, fast time course of symptoms

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12
Q

Hypothyroidism. mechanism?

A

Cause iodine overload –> suppress thyroid hormone synthesis (Wolff-Chaikoff effect).
ALSO amiodarone inhibits T4 -> T3 conversion

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13
Q

Hyperthyroidism. Mechanism?

A

Hyperthyroidism in patients with nodular thyroid disease OR latent graves disease (type 1) OR destructive thryoiditis with released hormone (type 2)

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14
Q

Amiodarone on thyroid.
Disorder: Decr. T4 -> T3. levels?

A

T4 incr.
T3 decr.
TSH normal or increased.

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15
Q

Amiodarone on thyroid.
Disorder: Decr. T4 -> T3. Tx?

A

No Tx needed

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16
Q

Amiodarone on thyroid.
Disorder: Inhibition of thyroid hormone synthesis. Levels?

A

T4 decr.
TSH incr.

17
Q

Amiodarone on thyroid.
Disorder: Inhibition of thyroid hormone synthesis. Tx?

A

Levothyroxine

18
Q

Amiodarone on thyroid.
Disorder: AIT type 1 (iodine-induced increased in thyroid hormone synthesis). levels?

AIT = amiodarone induced thyrotoxicosis

A

T3 incr.
T4 incr.
TSH decr.
RAIU decr.
increased vascularity on UG

19
Q

Amiodarone on thyroid.
Disorder: AIT type 1 (iodine-induced increased in thyroid hormone synthesis). Tx?

A

Antithyroid drugs

20
Q

Amiodarone on thyroid.
Disorder: AIT type 2 (destructive thyroiditis). levels?

A

T3 incr.
T4 incr.
TSH decr.
RAIU UNDETECTABLE
Decreased vascularity on UG

21
Q

Amiodarone on thyroid.
Disorder: AIT type 2 (destructive thyroiditis). Tx?

A

Glucocorticoids

STEP 2 Cardio + Renal (35 decks)

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