UTI Flashcards

1
Q

What distinguishes an upper UTI from a lower?

A

Upper includes the kidneys

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2
Q

Desribe ABU

A

Asymptomatic bacteremia that does not have sx

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3
Q

Gold standard for dx of UTI

A

culture

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4
Q

An urine analysis ain’t worth this?

A

sh*t

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5
Q

What things would one expect to find in a positive UA

A

bacteria, WBC, inflammatory cytokines

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6
Q

Tx for UTI

A

TMP-SMX - W alos Nitrofurantoin, M- FLouroquinolone

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7
Q

Causative agents for uncomplicated UTI?

A

E.coli (75%), S.Saprohyticus (5-15%)

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8
Q

Describe what makes a UTI complicated?

A

If it is caused by the use of a catheter, genetic abnormalities, obstruction, problems emptying bladder.

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9
Q

What percent of polynephritis is of blood origin?

A

10%

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10
Q

What virulence factors make E.coli the VIP of UTI’s?

A

surface adhesions faciliate binding to epithelial cells
P fimbriae - bind renal epithelial cells (polynephritis and bloodstream infections)
Type 1 pili - mediate binding to uroepithelial cells

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11
Q

List risk factors for uncomplicated UTI

A

intercourse, antibiotic use, diaphragm/spermicide use, recurrent UTI

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12
Q

List causes for complicated UTI.

A

E.coli, S.Aureus, Entercocci, yeast/fungal, Kliebassa, Pseudomonas

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13
Q

Triangle of pathogenesis for UTI? includes with factors?

A

Organism, host, enviroment

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14
Q

What are the 5 innate defenses against bacterial UTI

A
  1. urine flow
  2. urine chemistry- lysoyzmes and lactaferrin
  3. cell surface proteins
  4. normal flora
  5. secretory IgA
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15
Q

3 major source of UTI

A
  1. community acquired - GI flora
  2. Nosocomial - caths etc.
  3. Immune - Glomerulonephritis
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16
Q

Culture positive for gram(-) rod, MacConkey (+) and indole (+) indicates what organism causing UTI

A

e. Coli

17
Q

Culture positive for gram (+) cocci, catalase (+), coagulase (-), novobiocin (resitant)

A

staph. saprophyticus

18
Q

Which UTI causing organism would test indole(-)

A

Kleibsiella

19
Q

If a man or child has a UTI think this.

A

complicated

20
Q

young women incidence of uti per year is this

A

about 1 per year (0.5-0.7)

21
Q

What is the difference between selective and differential media?

A

selective inhibits growth of type of microbe

differential indicates via dye,etc the presence of certain products.