Urological Malignancy Flashcards
What is the main cancerous kidney tumour
Renal cell carcinoma (clear cell)
What are the two benign renal tumours
Oncocytoma
Angiomyolipoma
What are the two types of penile cancer
Squamous cell carcinoma
Carcinoma in situ
What are the two forms of testicular tumours
Seminoma
Teratoma
Where is the most common location for transitional cell carcinoma to occur
Renal pelvis
Bladder
Where is the most common location for renal cell carcinoma to occur
Renal parenchyma
What is the embryological form of a renal tumour
Nephroblastoma (Wilm’s tumour)
What investigation is good at identifying a fluid filled lesion
US
When is a contrast CT indicated in renal cysts
To identify any enhancement of the cysts - this increases the risk of being malignant
What is an angiomyolopoma made up of
Blood vessels
fat
muscle
What is Wunderlich’s syndrome
The risk of spontaneous haemorrhage - massive retroperitoneal bleeding that can be life threatening
Caused by an angiomyolipoma
Why might a fat poor angiomyolipoma need a biopsy and why is this a risky procedure
There is a risk of the tumour being a renal cell carcinoma - biopsy increases the risk of haemorrhage
What would be seen on CT in a oncocytoma
A central scar that goes out the way - necrosis in the centre of the tumour
What is a main feature that can be used to distinguish the difference between an oncocytoma and a renal cell cancer
Cancer has the ability to recruit new blood supply
Oncocytoma is benign and does not have this ability
What is the classic triad seen in the presentation of RCC
Loin pain
renal mass
haematuria
However, most are incidental findings on CT
Patients with Paraneoplastic syndromes commonly have what
Weight loss
anaemia
Hypertension
Hypercalcaemia
Who and at what age is most likely to develop RCC
Male: female - 2:1
65-75 years of age
What are the two main forms of renal cell carcinoma
Adenocarcinoma of the proximal convoluted tubule
Clear cell, papillary
What is the one diagnosis that everyone wants to rule out
Von Hippel-Lindau - genetic problem with major consequences
What is the key imaging technique required for a diagnosis of RCC
CT triple phase contrast