URINARY SYSTEM FINALS Flashcards
a protease important for regulation of
blood pressure by cleaving circulating angiotensinogen
to angiotensin I
Secretion of renin
a glycoprotein growth factor that stimulates erythrocyte production in red marrow
when the blood O2
level is low;
Secretion of erythropoietin
where nerves enter, the ureter exits, and blood and
lymph
hilum
Within
the hilum the upper end of the ureter expands as the _______ and divides into two or three major _____
renal pelvis and calyces
a darker stained region with many round corpuscles and
tubule cross sections
renal cortex
reabsorbs sodium through aldosterone
lack of sodium
reabsorbs water through antidiuretic hormone or arginine vasopressin
lack of water
consisting
mostly of aligned linear tubules and ducts
renal medulla
The
renal medulla in humans consists of 8-15 conical structures
called
renal pyramids
Each
pyramid plus the cortical tissue at its base and extending along
its sides constitutes a
renal lobe
The tip of each pyramid, called the
renal
papilla
what is the normal blood ph?
7.35-7.45
7.35
alkalosis
7.45
acidosis
release hydrogen into urine
acidic blood
release bicarbonate into urine
basic blood
Each kidney contains 1-4 million functional units called
nephrons
an initial dilated part enclosing a tuft
of capillary loops and the site of blood filtration, always
located in the cortex.
Renal corpuscle,
a long convoluted part, located
entirely in the cortex, with a shorter straight part that
enters the medulla.
Proximal tubule
, in the medulla, with a
thin descending and a thin ascending limb.
loop of henle
consisting of a thick straight part ascending from the loop of Henle back into the cortex and a
convoluted part completely in the cortex.
Distal tubule
a short minor part linking the
nephron to collecting ducts.
Connecting tubule
e is an inherited disorder in which
normal cortical organization of both kidneys is lost due to the
formation of multiple, large, fluid-filled cysts.
Polycystic kidney disease
Around the renal pelvis, these
arteries branch further as the _________ which
extend between the renal pyramids toward the corticomedullary junction
interlobar arteries
Here the interlobar arteries divide
again to form the ______, which run in an arc along
this junction at the base of each renal pyramid
arcuate arteries
which divide to form a plexus of capillary loops called the
glomerulus
Blood leaves the glomerular capillaries, not
via venules, but via
efferent arterioles
which at once branch
again to form another capillary network, usually the
peritubular capillaries
parallel tassel-like bundles of capillary loops called the
vasa recta
, by which water and solutes in the blood
leave the vascular space and enter the lumen of the
nephron.
Filtration
by which substances move from
epithelial cells of the tubules into the lumens, usually after uptake from the surrounding interstitium and
capillaries.
Tubular secretion
by which substances move from
the tubular lumen across the epithelium into the interstitium and surrounding capillaries
Tubular reabsorption
At the beginning of each nephron is a renal corpuscle, about
200 μm in diameter and containing a tuft of glomerular capillaries, surrounded by a double-walled epithelial capsule called
the
glomerular (Bowman) capsule
. Between
the two capsular layers is the
capsular (or urinary) space,
Each renal corpuscle has a
vascular pole
where the proximal convoluted
tubule (PCT) begins
tubular pole
The visceral layer of a renal corpuscle consists of unusual
stellate epithelial cells called
podocytes
From the cell body of
each podocyte several
primary processes
Spanning adjacent pedicels and bridging the slit pores are
zipper-like
slit diaphragms
Slit diaphragms are
modified and specialized occluding or tight junctions composed
of
nephrins
is an indicator of
many potential kidney disorders.
Proteinuria
In addition to capillary endothelial cells and podocytes,
renal corpuscles also contain
mesangial cells
small branches are called _________ arise from the MAJOR CALYCES
MINOR CALYCES
established by the nephron
loop and vasa recta is an important aspect of renal physiology in humans
countercurrent multiplier system