ADIPOSE TISSUE MIDTERM Flashcards
Connective tissue in which fat-storing cells or adipocytes predominate is called
adipose tissue
the more common type specialized for fat storage,
consists of cells each containing one large cytoplasmic droplet of whitish-yellow fat
White adipose tissue
contains cells
with multiple lipid droplets interspersed among abundant
mitochondria, which helps give this tissue a darker appearance
Brown adipose tissue
With the single large droplets of triglycerides, white adipocytes are also called
unilocular
Dietary fats brought to the cells via the circulation as
chylomicrons
■ Lipids synthesized in the liver and transported in blood
with
very low-density lipoproteins (VLDLs),
In adipose tissue both chylomicrons and VLDLs are
hydrolyzed at the luminal surfaces of blood capillaries by _________, an enzyme synthesized by the adipocytes and
transferred to the capillary cell membrane
lipoprotein lipase
_________ released in the adrenal gland
and by postganglionic sympathetic nerves in adipose tissue activates a _________ that breaks down triglycerides at the surface of the stored lipid droplets
Norepinephrine - hormone-sensitive lipase
Hormonal activity of white adipocytes themselves
includes production of the 16-kDa polypeptide hormone
leptin
Like other connective tissue, skeletal and muscle cells, adipocytes
develop from mesenchymal stem cells. Adipose development
first produces _______
preadipocytes
_________ is very often associated with agerelated metabolic changes and may involve reduced activity of the hormone-sensitive lipases of adipocytes, causing
less effective fat mobilization out of the cells.
Adult-onset obesity
Brown adipocytes contain many small lipid
inclusions and are therefore called ________
multilocular
The small lipid droplets, abundant mitochondria, and rich
vasculature all help mediate this tissue’s principal function of ________ and warming the blood.
heat production
The main function of these multilocular adipose cells is to
produce heat by nonshivering ________
thermogenesis.
Fatty acids released in adipocytes of brown fat are metabolized in
mitochondria of these cells for thermogenesis rather than ATP synthesis, using ________
uncoupling protein-1