Urinary system Flashcards
What metabolic waste products are exreted in the urine?
- Urea
- Creatinine
- Uric acid
- Bilirubin
What does urea come from?
The breakdown of amino acids
What does creatnine come from?
The breakdown of creatine phosphate in muscles
What does uric acid come from?
The catabolism of nucleic acids
What does billirubin come from?
The catabolism of hemoglobin
Generally, how does the urinary system regulate blood volume?
By conserving or elminating water in urine
What controls blood composition?
- Na
- K
- Ca
- Cl
- Phosphate ions
Generally, how does the urinary system regulate blood pressure?
Secretion of renin
Generally, how does the urinary sytem regulate blood pH?
- Extretion of H+ions in urine
- Conservation of bicarbonate ions in blood
Generally, how does the urinary system regulate blood glucose levels?
By producing and releasing glucose into the blood (much like the liver)
How does the urinary sytem regualte calcium homeostaisis?
By producing calcitrol (active form of vitamin D)
What does erythorpoietin cause in the urinary system?
Stimulates the production of RBC
Is sodium an intercellular or extracellular fluid?
Extracellular
Is potassium an intracellular fluid or an extracellular fluid?
Intracellular fluid
What ion repolarizes the membrane potential?
Potassium
What kidney is more inferior and why?
The right kidney is more inf. because of the liver
What part of the kidney is most posterior?
The superior part
What vertebral level are the kidneys located at?
T12-L3
How do we best demonstrate the right kidney?
LPO oblique of 30 degrees to make it parrellel to the IR
Which way are the kidneys obliqued naturally?
Obliqued 30 degrees anteriorly
What are the kidneys protected by?
Ribs 11 and 12
In situ, what structures are located anterior to the right kidney?
- Right lobe of liver
- Descending duodenum
- Hepatic flexure
- Ascending colon
In situ, what structures are located anterior to the left kidney?
- Tail of pancreas
- Stomach
- Splenic flexure
- Descending colon
What type of exam is this?
KUB contrast
Label 3-6
- Ascending colon
- Descending colon
- Abominal aorta
- IVC
What is the renal capsule?
The inner most layer surrounding the kidney
What are the 3 layers that surround the kidney from deep to superficial?
- Renal capsule
- Adipose capsule
- Renal facia
What is the adipose capsule?
The middle layer surrounding the kidney
What is the function of the adpose capsule?
Protection and to help hold the kidney in place
The dropping of the kidney by 2in/5cm from supine to erect is refered to as what?
Ptosis
What body type is ptosis greatest with? Why?
Asthenic body types because they have the least amount of fat to hold the kidneys in place
What is the renal capsule?
The outermost, dense tissue layer that surrounds the kidneys
What does the renal fascia connect the kidney to?
- Abdominal wall,
- lumbar vertebrae,
- diaphragm
What is the renal cortex?
The outer layer of the inside of the kidneys
What is the renal column?
The anchor for cortex located between the renal pyrimids that allow for the passage way for vessels
What is the renal medulla?
The inner layer of the kidney that consists of series of pryimids
What are the renal pryramids? How many do we have on average?
Cone-shaped structures located within the medulla
-We have 8-18 on average
What is the renal papilla?
The distal part of the pryamids that drain into the minor calyces
How many minor calyces do we have on average?
8-18
What do the minor calyces drain into?
The major calyces
How many major calyces do we have on average?
2-3
What do the major calyces comine to form?
Combine to form the renal pelvis
What is the renal hilum?
The indented area on the medial side of the kidney
What does the renal hilum contain?
- Renal artery
- Renal vein
- Ureter
- Nerves
- Lymphatics
What are the 2 main parts of the nephron?
- Renal corpuscle
- Renal tubule
How many nephrons do we have on average?
1 million/kidney
What is the nephron? Where is it located?
The functional unit of the kidney located in the renal cortex AND the renal medulla (pyramid)
What part of the nephron is located in the medulla?
The loop of henle
During inspiration, which way does the kidney move?
Down
During expiration, which way does the kidney move?
Up
What is a renal lobe?
1 pyramid that consists of everything from the minor calyx to the renal cortex
How many renal pelvis’ do we have?
1
How many ureters do we have?
Only 1
What does the renal pelvis drain into?
The ureter
What are the 2 parts of the renal corpuscle in the nephron?
- Glomerulus
- Bowmans capsule/glomerular capsule
What occurs in the renal corpuscle?
Blood plasma is filtered from glomerular capillaries to the the glomerular capsule/bowmans
What is the glomerulus?
A network of capillaries surrounded by the bowmans capsule
What is the bowmans capsule?
A double-walled cup that surrounds the glomerulus
What are the 3 parts of the renal tubule?
- Proximal convoluted tubule
- Loop of henle (nephron loop)
- Distal convoluted tubule
What is the pathway of blood starting at the renal arteries?
- Renal arteries
- Segmental artery
- Interlobar artery
- Arcuate arteries
- Cortical radiatiate arteries
- Afferent arterterioles
- Glomerulus
- Efferent arteriole
- Peritubular capillaries
- Cortical radiate veins
- Arcuate veins
- Interlobar veins
- Renal vein
What percentage of the resting cardiac output do the kidneys recieve?
20-25%
Which renal arteries is longer?
The right
How many renal arteries do we have in total (both sides)
2 in total
How many segmental arteries are there?
Supplies one to each segment
Where does the the segmental arteries and interlobar arteries pass through?
The renal columns
Where are the arcuate arteries located?
The arch between the renal medulla and cortex
Where do the cortical radiate arteries radiate towards?
Radiate outwards into the renal corex
How many afferent arterioles do we have?
1 per nephron
What is the function of the efferent arteriole?
Carries blood away from the glomerulus
Where are the peritubular capillaries located?
They surround the tubular parts of the nephron
Which arteriole is larger; the efferent or the afferent?
The afferent
What arteriole has higher pressrure; efferent or afferent? Why?
The afferent arteriole because of the increase in its size
Check
What are the 2 types of nephrons?
- Cortical nephrons
- Juxtamedullary nephrons
What percentage do the cortical nephrons make up?
80-85%
What percentage of nephrons do the juxtamedullary nephrons make up?
15-20%
Where is the renal corpuscle located in the kidney?
Lies in the outer part of the renal cortex
True or false?
The jextamedullary nephrons have a short loop of henle.
False; long
True or false?
The cortical nephrons have a short loop of henle.
True
Where are the renal corpuscles in juxtaglomerular nephrons?
Deep in the renal cotex (close to the medulla)
What additional blood supply do juxtaglomerular nephrons have that cortical nephrons do not?
The vasa recta
What are the 2 parts of the loop of henle in juxtaglomerular nephron?
- Thick portion
- Thin portion
What is the purpose of the juxtaglomerular nephrons having a long loop of henle?
Aloows the kidneys to excrete very dilute or very concentrated urine
True or false?
The glomerulus is very leaky and lets out allows all of the solutes to leak out into PCT.
False; it is very leaky but does not allow blood cells to leak out
What are the 2 layers to the glomerulus?
- Parietal
- Visceral
What is located between the visceral and parietal layers of the bowmans capsule?
The capsular space where filtrate is collected
What is blood called as it goes from the glomerulus to the bowmans capsule?
Filtrate
What are the two parts of the loop of henle?
- Decending loop
- Ascending loop
Where is the macula densa located?
On the acending loop in contact with the afferent arteriole
What are the juxtaglomerular cells and where are they located?
They are smooth muscle fibers located along the sides of the afferent arteriole and the macula densa.
(next to the glomerulus)
What is the juxtaglomerular complex?
The macula densa+juxtaglomerular cells that helps to regulate blood pressure within the kidney
What are the two cell types within the distal convoluted tubule?
- Prinicpal cells
- Intercalated cells
What is the function of the prinicpal cells?
They are the receptors for anti duretic hormone (ADH) and aldostrone