Upper GI II Flashcards
________ opens into bottom of gastic pit
Narrow isthmus
______ of the gastric gland extends into the lamina propria
Fundus (base)
Cells of the gastric gland
- mucous neck cells
- Stem cells in neck
- Chief cells (zymogenic cells)
- Parietal cells (oxyntic cells)
- Enteroendocrine Cells (APUD cells)
Mucous neck cells of the gastric glands secrete
soluble mucous
Chief cells (zymogenic cells) secrete
Pepsinogen
Parietal cells (oxyntic cells) manufacture _______ and secrete ______
Manufacture HCl (note that they secrete H+ and Cl-) They secrete intrinsic factor
Enteroendocrine cells (APUD cells) function of gastric glands
- secrete hormones
- Amine Precursor uptake and decarboxylation
Parietal cells are unique cell of the
gastric gland
Histological characteristics of parietal cells
Large pyramidal shaped, eosinophilic cell
Parietal cells produce ______ and secrete ____-
Produce HCl
Secrete intrinsic factor
Parietal cells generate hydrogen ion from _______ similar to osteoclast
carbonic acid
Parietal cells have prominent __________ lined by ______
Parietal cells have a prominent intracellular canaliculi lined by microvilli
_________ of the parietal cells are part of exocytosis-endocytosis funciton
Turbulovesicle pools
Function of gastric intrinsic factor secreted by parietal cells
necessary for absorption of Vitamin B12 by the ileum
Chief cells secrete
pepsinogen