Liver Flashcards
Space of Mall is continuous with
space of Disse
The space of Mall drains into
lymphatics
________ covers the surface of the liver except at the diaphragmatic attachment
Glisson’s thin capsule of FECT
What are the three types of Hepatic Lobules
- Classic
- Portal
- Liver acinus
Structure of Classic Hepatic Lobule
- Central venule is in the center of the lobule
- Portal triads are at the angles
Structure of Portal hepatic lobule
- Three central venules of adjacent lobules form a triangle
- Portions of the bile canaliculi of the three lobules drain into the same bile duct
where are portal triads found
at the angles (corners) of classic lobule
What are the three components of the portal triad
- Branch of hepatic artery (arteriole)
- Branch of portal vein (venule)
- Bile duct (ductule)
Liver acinus includes ____ zones defined by hepatic tissue receiving blood from a ________________ to opposite ________
3, branch of the hepatic artery, to opposite central veins
A characteristic of liver acinus are metabolic gradients that extend from _______ to _____
hepatic triad, central vein
Hepatocyte
- Polyhedral in form
- Central nucleus with one or more nucleoli
- cytoplasm may contain glycogen, fat droplets, and pigment granules
- Basolateral domain
- Microvilli
- Faces space of Disse
- involved in
- absorption of blood-borne substances
- Secretion of plasma proteins
- Apical Domain:
- Borders bile canaliculus
Lining of hepatic sinusoids
- Fenestrated endothelial cells
- Discontinuous basal lamina
Where are perisinusoidal cells found
in the space of Disse
Perisinusoidal cells store
Vitamin A
Perisinusoidal cells produce
collagen fibers and extracellular matrix components