Integument II Flashcards

1
Q

Sebaceous glands

A
  • Holocrine glands
  • branched acinar glands with short ducts
  • found everywhere except palms and soles
  • continuously produce sebum
    • released into hair follicle
  • Growth is stimulated at puberty by sex hormones
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2
Q

Sebaceous glands continually secrete

A

Sebum

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3
Q

Sebum is released into

A

hair follicles

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4
Q

Sebaceous glands use what type of secretion

A

holocrine

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5
Q

Sweat (sudoriferous) glands are what type of glands (secretion)

A

-both merocrine and apocrine glands

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6
Q

Merocrine sweat (sudoriferous) glands

A
  • Coiled, simple tubular secretory portions:
    • Lined by simple epithelium
    • Apical dark secretory cells secrete glycoproteins
    • Basal clear cells secrete water and electrolytes
    • Myoepithelial cells (found between the basal lamina and the basal domain of clear cells)
  • Duct system consists of stratified cuboidal epithelium except in epidermis
  • Cholinergic endings
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7
Q

Apocrine sweat (sudoriferous) glands

A
  • found in labia major, areola, and axillary and anal regions
  • secretions are thicker and more viscous than merocrine types
  • excretory duct opens into hair follicle
  • Adrenergic innervation
  • inactive until puberty
  • Special types: Ceruminous glands, Glands of Moll
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8
Q

What are the two special types of apocrine sweat glands

A
  • Ceruminous glands

- Glands of Moll

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9
Q

apocrine sweat glands have what type of secretion

A

Although called apocrine the name is a incorrect interpretation that the apical domain of the secretory cells is shed during secretion. These sweat glands release their secretion by a merocrine process

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10
Q

Development of hair follicle

A

Develop from epidermis as elastic, keratinized threads

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11
Q

Components of hair follicle

A
  • Root
  • Free shaft
  • Hair follicle
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12
Q

____ glands and ______ muscles are associated with hair follicles

A

sebaceous glands, arrector pili

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13
Q

Hair bulb

A
  • Expanded lower part of hair follicle
  • Matrix
  • Vascularized dermal papilla
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14
Q

epithelial cells covering the apex of the dermal papilla give rise to the _____ of the hair. cells at the sides give rise to the hair ____.cells at the margin form the _____

A

Medulla of hair, Hair cortex, cuticle

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15
Q

Patients with _____ syndrome have silvery hair because of a mutation in the myosin Va gene involved in the transport of melanin-containing melanosomes

A

Griscelli

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16
Q

The external root sheath of hair follicle

A

down growth of epidermis

17
Q

Internal root sheath of hair follicle

A
  • Generated by bulb
  • Layers:
    • Henle’s layer (outermost)
    • Huxley’s layer
    • Cuticle
      - Interlocks with cuticle of hair shaft
18
Q

What are the layers of the hair shaft

A
  • medulla (innermost
  • Cortex
  • Cuticle
19
Q

What cells can reestablish epidermis in severely burned patients

A

Keratinocyte stem cells

20
Q

Migration pathways for keratinocyte stem cells

A
  • bulb-epidermis stem cell pathway
  • bulb-sebaceous gland stem cell pathway
  • bulb-hair stem cell pathway
21
Q

Signaling pathways for Keratinocyte stem cells

A
  • Wnt signaling pathway

- Notch signaling pathway