Untitled Deck 3 Flashcards
Dysphasia lusoria?
Compression of oesophagus due to aberrant right subclavian artery
BRCA1?
Chromosome 17
BRCA2?
Chromosome 13
Small cell lung cancer?
In smokers
Adenocarcinoma of the lung?
Most common in never smokers
Upper PSA limit?
(age-20)/10
Takayasu arteritis?
Large vessel granulomatous vasculitis
Buerger’s disease?
Segmental thrombotic occlusions of small and medium sized vessels
Corkscrew shaped collateral vessels seen
Leriche syndrome?
Atheromatous disease of iliac vessels
Buttock claudication and impotence
Primary sclerosing cholangitis is a risk factor for?
Cholangiocarcinoma
Marfan syndrome?
AD, defect in fibrillin gene on chromosome 15
Mirel scoring?
Stratifies risk of fracture for bone metastasis
Odynophagia?
Painful swallowing
Oncogenes?
sis, myc, RET, Src, Ras
Hodgkin lymphoma?
Reed Sternberg cells (2 nuclei)
Ann Arbor staging system?
For staging of Hodgkin lymphoma
Nodes on one or both sides of the diaphragm
MEN type 1 most common presentation?
Hypercalcemia
MEN 1 3Ps?
Parathyroid, pancreas, pituitary
MEN 1 gene?
MENIN gene chromosome 11
MEN 2 and 3 gene?
RET gene chromosome 10
Wallerian degeneration?
Axonal degeneration distal to the site of surgery
Axonotmesis?
Axon damaged, myelin sheath preserved
Neurotmesis?
Axon and myelin sheath damaged
Metaplasia?
Cell type conversion
Why the different position of recurrent laryngeal n on both sides?
Due to aortic arches V and VI disappearing on the right
Loops under right subclavian vs on the left loops under VI/ligamentum arteriosum
Superior laryngeal n?
Innervates cricothyroid, high pitch and singing
Inferior laryngeal n?
Innervates intrinsic larynx muscles, vocal cords, speech, swallowing
Trachea lining
Lined by ciliated columnar epithelium
PT?
Vitamin K dependent factors 2, 7, 9, 10
APTT?
Factors 8, 9, 11, 12
Jaundice and vit K?
Impairs production of Vitamin K