Untitled Deck 1 Flashcards

1
Q

Adrenaline acts on which receptors?

A

a1,2, b1,2

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2
Q

Adrenaline causes vasoconstriction on what receptor?

A

A1

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3
Q

What is the main path of coagulation?

A

extrinsic pathway

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4
Q

Which factor activation is inhibited by heparin?

A

factors 2,9,10,11

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5
Q

Where do both coagulation pathways meet?

A

in factor 10 activation

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6
Q

What is the role of thrombin?

A

converts fibrinogen to fibrin

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7
Q

What is fibrinolysis?

A

plasminogen converted into plasmin to break down fibrin

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8
Q

What is the cardiac index formula?

A

Cardiac index = Cardiac output / body surface area.

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9
Q

What is the role of angiotensin II?

A

vasoconstriction

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10
Q

What is atropine’s action?

A

Muscarinic receptor antagonist (inhibits parasympathetic action)

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11
Q

What are examples of TNF alpha inhibitors?

A

infliximab, adalimumab, etanercept

(RA and Chrons)

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12
Q

What are examples of anti-VEGF drugs?

A

Bevacizumab

(colorectal cancer)

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13
Q

What is an example of a HER receptor drug?

A

Transtuzumab

(breast cancer)

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14
Q

What is an example of an IL2 binding drug?

A

Basiliximab

(renal transplant)

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15
Q

What is the use of cetuximab?

A

Colorectal cancer

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16
Q

What is the ERCP prep?

A

clotting check, ABx, vit K if jaundiced

17
Q

What is the OGD prep?

A

NBM for 6h

18
Q

What is the flexible sigmoidoscopy prep?

A

Phosphate enema 30min pre procedure

19
Q

What is the colonoscopy prep?

A

check U&E, if normal then oral purgatives

20
Q

What is the lignocaine dose/adrenaline?

A

3mg/kg / 7mg/kg

21
Q

What is the bupivacaine dose/adrenaline?

A

2mg/kg both

22
Q

What is the prilocaine dose/adrenaline?

A

6mg/kg / 8mg/kg

23
Q

What is an acute dystonic reaction?

A

resting tremor, bradykinesia, involuntary spasm movements

24
Q

What is the cause of an acute dystonic reaction?

A

antidopaminergic drug such as metoclopramide

25
Q

What is the treatment for an acute dystonic reaction?

A

benzhexol or procyclidine

26
Q

What are complications of colorectal surgery?

A

infection, bleeding, anastomotic leak

27
Q

What does cryoprecipitate contain?

A

factor 8, factor 13, vWF, fibrinogen

28
Q

mid point of inguinal ligament

A

asis to pubic tubercle half way (this is the deep ring)

29
Q

mid inguinal point

A

asis to pubic symphysis - surface marking of femoral pulse

30
Q

tetraology of fallot

A
  • ventricular septal defect
  • pulmonary stenosis
  • right ventricular hypertrophy
  • overriding aorta
31
Q

superficial partial thickness burn

A

moist
erythematous
blistering
blanching

32
Q

SUFE

33
Q

Perthes

A

boys 4-8yo, (boys with low birth weight and ADHD)