Untitled Deck 1 Flashcards
Adrenaline acts on which receptors?
a1,2, b1,2
Adrenaline causes vasoconstriction on what receptor?
A1
What is the main path of coagulation?
extrinsic pathway
Which factor activation is inhibited by heparin?
factors 2,9,10,11
Where do both coagulation pathways meet?
in factor 10 activation
What is the role of thrombin?
converts fibrinogen to fibrin
What is fibrinolysis?
plasminogen converted into plasmin to break down fibrin
What is the cardiac index formula?
Cardiac index = Cardiac output / body surface area.
What is the role of angiotensin II?
vasoconstriction
What is atropine’s action?
Muscarinic receptor antagonist (inhibits parasympathetic action)
What are examples of TNF alpha inhibitors?
infliximab, adalimumab, etanercept
(RA and Chrons)
What are examples of anti-VEGF drugs?
Bevacizumab
(colorectal cancer)
What is an example of a HER receptor drug?
Transtuzumab
(breast cancer)
What is an example of an IL2 binding drug?
Basiliximab
(renal transplant)
What is the use of cetuximab?
Colorectal cancer
What is the ERCP prep?
clotting check, ABx, vit K if jaundiced
What is the OGD prep?
NBM for 6h
What is the flexible sigmoidoscopy prep?
Phosphate enema 30min pre procedure
What is the colonoscopy prep?
check U&E, if normal then oral purgatives
What is the lignocaine dose/adrenaline?
3mg/kg / 7mg/kg
What is the bupivacaine dose/adrenaline?
2mg/kg both
What is the prilocaine dose/adrenaline?
6mg/kg / 8mg/kg
What is an acute dystonic reaction?
resting tremor, bradykinesia, involuntary spasm movements
What is the cause of an acute dystonic reaction?
antidopaminergic drug such as metoclopramide
What is the treatment for an acute dystonic reaction?
benzhexol or procyclidine
What are complications of colorectal surgery?
infection, bleeding, anastomotic leak
What does cryoprecipitate contain?
factor 8, factor 13, vWF, fibrinogen
mid point of inguinal ligament
asis to pubic tubercle half way (this is the deep ring)
mid inguinal point
asis to pubic symphysis - surface marking of femoral pulse
tetraology of fallot
- ventricular septal defect
- pulmonary stenosis
- right ventricular hypertrophy
- overriding aorta
superficial partial thickness burn
moist
erythematous
blistering
blanching
SUFE
obese
Perthes
boys 4-8yo, (boys with low birth weight and ADHD)