Unit II Ketogenesis Flashcards
Ketone bodies are produced in response to low/no?
carbohydrates
What is the location of ketogenesis?
liver mitochondrial matrix
What are the functional ketone bodies?
acetoacetate and Beta-hydroxybutyrate
What ketone body is exhaled as a by-product?
acetone
What substances can make ketone bodies?
acetyl CoA and ketogenic acmino acids
The liver comsumes butdoes not produce ketone bodies. True or false?
False, the liver ONLY produces ketone bodies
What is considered that rate limiting step of HMG CoA synthase?
rate limiting step
What would stimulate mitchondiral HMG CoA Synthase?
prolonged fasting, no/low carbohydrates
Cytosolic HMG CoA synthase is used in what pathway?
cholesterol synthesis
No carbs, low ATP, and in the liver would stimulate what pathway?
ketogenesis
High carbs, lots of ATP, and in the cytosol would stimulate what pathway?
cholesterol synthesis
Besides low carbs and starvation, what would create a high concentrationof ketones in the system?
accelerated Beta-oxidation and uncontrolled Type I diabetes
In ketogensis glucagon stimulates?
fat burning
In ketogensis glucagon inhibts?
liver glycolysis
Acetyl CoA inbihits whatin ketogenesis?
pyruvate dehydrogenase
